"RIV/61388955:_____/05:00000699!RIV06-AV0-61388955" . "DNA condensation is accompanied by dramatic decrease in the volume occupied by DNA molecule and is used in non-viral gene therapy. Method of fluorescence correlation spectroscopy (FCS), which provides the information on the diffusion properties of an object of interest by analyzing the fluctuations of fluorescence signal collected from confocal volume, was found to be suitable for minitoring the process of DNA condensation. In this article we summarize the results achieved in doc. Hof\u2019s group in years 2002-2005. There are mentioned parameters gained by FCS, which are most convenient for describing the DNA condensation, suitable fluorescence dyes and various condensation agents." . . "DNA condensation characterised by fluorescence correlation spectroscopy (FCS)" . . "DNA condensation characterised by fluorescence correlation spectroscopy (FCS)"@en . "PL - Polsk\u00E1 republika" . . . . . . "Hof, Martin" . "DNA condensation characterised by fluorescence correlation spectroscopy (FCS)"@en . "518474" . "DNA kondenzace charakterizovan\u00E1 pomoc\u00ED fluorescen\u010Dn\u00ED korela\u010Dn\u00ED spektroskopie (FCS)"@cs . "DNA condensation characterised by fluorescence correlation spectroscopy (FCS)" . "Blagbrough, I. S." . . "23;25" . "Kral, Teresa" . . "RIV/61388955:_____/05:00000699" . "Cellular & Molecular Biology Letters" . . . . . "Adjimatera, N." . "1425-8153" . "DNA condensation is accompanied by dramatic decrease in the volume occupied by DNA molecule and is used in non-viral gene therapy. Method of fluorescence correlation spectroscopy (FCS), which provides the information on the diffusion properties of an object of interest by analyzing the fluctuations of fluorescence signal collected from confocal volume, was found to be suitable for minitoring the process of DNA condensation. In this article we summarize the results achieved in doc. Hof\u2019s group in years 2002-2005. There are mentioned parameters gained by FCS, which are most convenient for describing the DNA condensation, suitable fluorescence dyes and various condensation agents."@en . "Kral, Teresa" . . "2"^^ . "Langner, M." . "[2749BA15273C]" . . "DNA kondenzace je doprov\u00E1zen\u00E1 dramatick\u00FDm zmen\u0161en\u00EDm objemu zab\u00EDran\u00FDm molekulou DNA a na\u0161la \u0161irok\u00E9 vyu\u017Eit\u00ED v non-viri\u00E1ln\u00ED genov\u00E9 terapii. Metoda fluorescen\u010Dn\u00ED korela\u010Dn\u00ED spektroskopie, kter\u00E1 pomoc\u00ED anal\u00FDzy fluktuac\u00ED fluorescen\u010Dn\u00EDho sign\u00E1lu sb\u00EDran\u00E9ho z konfok\u00E1ln\u00EDho objemu poskytuje informace o dif\u016Fzn\u00EDch vlastnostech sledovan\u00E9 l\u00E1tky, se jev\u00ED jako vhodn\u00E1 pro sledov\u00E1n\u00ED kondenzace DNA. V t\u00E9to pr\u00E1ci jsou shrnuty v\u00FDsledky dosa\u017Een\u00E9 v laborato\u0159i doc. Hofa v letech 2002-2005. Jsou zm\u00EDn\u011Bny parametry z\u00EDskan\u00E9 pomoc\u00ED FCS, kter\u00E9 nejl\u00E9pe popisuj\u00ED stupe\u0148 DNA kondenzace, vhodn\u00E1 fluorescen\u010Dn\u00ED barviva a l\u00E1tky, je\u017E zp\u016Fsobuj\u00ED DNA kondenzaci."@cs . . "DNA kondenzace charakterizovan\u00E1 pomoc\u00ED fluorescen\u010Dn\u00ED korela\u010Dn\u00ED spektroskopie (FCS)"@cs . "10" . "5"^^ . . "-" . "DNA condensation; fluorescence; DNA"@en . "3"^^ . "P(GA203/05/2308), Z(AV0Z40400503)" .