. . . . "Simple water-soluble lanthanum and europium complexes are effective at detecting neutral sugars as well as glycolipids and phospholipids. In solutions at physiologically relevant pH the fluorescent lanthanum complex binds neutral sugars with apparent binding constants comparable to those of arylboronic acids. interference from commonly occurring anions is minimal. The europium complex detects sialic acid-containing gangliosides at pH 7.0 over an asialoganglioside. This selectivity is attributed, in large part, to the cooperative complexation of the oligosaccharicle and sialic acid residues to the metal center, based on analogous prior studies. In MeOH, lysophosphatidic acid (LPA), a biomarker for several pathological conditions including ovarian cancer, is selectively detected by the europium complex. LPA is also detected via a fluorescence increase in human plasma samples. The 2-sn-OH moiety of LPA plays a key role in promoting binding to the metal center. Other molecules found in common brain gangli" . . "Pruet, J." . . . "Simple water-soluble lanthanum and europium complexes are effective at detecting neutral sugars as well as glycolipids and phospholipids. In solutions at physiologically relevant pH the fluorescent lanthanum complex binds neutral sugars with apparent binding constants comparable to those of arylboronic acids. interference from commonly occurring anions is minimal. The europium complex detects sialic acid-containing gangliosides at pH 7.0 over an asialoganglioside. This selectivity is attributed, in large part, to the cooperative complexation of the oligosaccharicle and sialic acid residues to the metal center, based on analogous prior studies. In MeOH, lysophosphatidic acid (LPA), a biomarker for several pathological conditions including ovarian cancer, is selectively detected by the europium complex. LPA is also detected via a fluorescence increase in human plasma samples. The 2-sn-OH moiety of LPA plays a key role in promoting binding to the metal center. Other molecules found in common brain gangli"@en . "482895" . "gangliosides; lysophosphaticlic acid; salophenes; saccharides"@en . "P(GA203/06/1038), P(LC512), Z(MSM6046137307)" . "Lanthanide complexes as fluorescent indicators for neutral sugars and cancer biomarkers"@en . "1091-6490" . "RIV/60461373:22340/06:00016747" . . "Lanthanide complexes as fluorescent indicators for neutral sugars and cancer biomarkers" . . "Escobedo, J." . "RIV/60461373:22340/06:00016747!RIV07-MSM-22340___" . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "2" . "22340" . "Jednoduch\u00E9 ve vod\u011B rozpustn\u00E9 komplexy lanthanu a europia jsou \u00FA\u010Dinn\u00E9 p\u0159i detekci neutr\u00E1ln\u00EDch cukr\u016F stejn\u011B jako glykolipid\u016F a fosfolipid\u016F V roztoc\u00EDch s pH bl\u00EDzk\u00FDm fyziologick\u00E9mu se fluorescen\u010Dn\u00ED komplexy lanthanu v\u00E1\u017Eou na neutr\u00E1ln\u00ED cukry s vazebnou konstantou srovnatelnou s arylboronov\u00FDmi kyselinami."@cs . "[E233513C595F]" . "2"^^ . "9756-9760" . . "Crowe, W." . . . . "103" . . "Lanthanidov\u00E9 komplexy jako fluorescen\u010Dn\u00ED indik\u00E1tory pro neutr\u00E1ln\u00ED cukry a rakovinn\u00E9 biomarkery"@cs . . "Wang, W." . "Fakayode, S." . . "5"^^ . "Warner, I." . "10"^^ . "Lanthanide complexes as fluorescent indicators for neutral sugars and cancer biomarkers"@en . . "Lanthanide complexes as fluorescent indicators for neutral sugars and cancer biomarkers" . "Rus\u00EDn, Oleksandr" . "Lanthanidov\u00E9 komplexy jako fluorescen\u010Dn\u00ED indik\u00E1tory pro neutr\u00E1ln\u00ED cukry a rakovinn\u00E9 biomarkery"@cs . . . "Alpt\u00FCrk, O." . . "Strongin, R." . "Proceedings of the National Academy of Sciences of U.S.A" . "Kr\u00E1l, Vladim\u00EDr" .