"C8-Alkenylpurines were synthesized starting from purin-8-yl(allyl) acetates using Pdcatalyzed allylic substitution. The described protocol allows, by reaction of purin-8-yl(allyl) acetates with stabilized nucleophiles, an access to novel (E)-8-alkenylpurine derivatives under Pd2dba3?CHCl3 catalysis in dry THF in yields ranging from 31 to 76%. A wide range of nucleophiles showed exclusive E-alkene formation, however, ethyl nitroacetate gave mixture of E/Z-alkenes. On contrary, purin-2-yl(allyl) acetates reacted smoothly only with dimethyl malonate."@en . "3"^^ . . "Pd-Catalyzed Allylic Substitution of Purin-8-yl(allyl) Acetate: Route to (E)-Alkenylpurines" . "Dvo\u0159\u00E1k, Dalimil" . . "Nucleophilic substitution; Palladium; Heterocycles"@en . . . "Collection of Czechoslovak Chemical Communications" . "C8-Alkenylpurines were synthesized starting from purin-8-yl(allyl) acetates using Pdcatalyzed allylic substitution. The described protocol allows, by reaction of purin-8-yl(allyl) acetates with stabilized nucleophiles, an access to novel (E)-8-alkenylpurine derivatives under Pd2dba3?CHCl3 catalysis in dry THF in yields ranging from 31 to 76%. A wide range of nucleophiles showed exclusive E-alkene formation, however, ethyl nitroacetate gave mixture of E/Z-alkenes. On contrary, purin-2-yl(allyl) acetates reacted smoothly only with dimethyl malonate." . "\u0160i\u0161kov\u00E1, Miroslava" . . "16"^^ . "3"^^ . "P(GA203/09/1552), P(LC06070)" . "Tobrman, Tom\u00E1\u0161" . . . . . . . "000289355200007" . "219774" . . "Pd-Catalyzed Allylic Substitution of Purin-8-yl(allyl) Acetate: Route to (E)-Alkenylpurines" . . . "10.1135/cccc2011030" . "[FD4DC48BD59C]" . "RIV/60461373:22310/11:43892715!RIV12-MSM-22310___" . "22310" . . "CZ - \u010Cesk\u00E1 republika" . "76" . . "RIV/60461373:22310/11:43892715" . . "Pd-Catalyzed Allylic Substitution of Purin-8-yl(allyl) Acetate: Route to (E)-Alkenylpurines"@en . "Pd-Catalyzed Allylic Substitution of Purin-8-yl(allyl) Acetate: Route to (E)-Alkenylpurines"@en . . "4" . . "0010-0765" .