"4289-4291" . . . "6-Magnesiated Purines: Preparation and Reaction with Aldehydes" . . . "P(GA203/03/0035)" . . . . . "6-Magnesiated Purines: Preparation and Reaction with Aldehydes"@en . "5" . . . "636887" . "RIV/60461373:22310/03:00008311!RIV/2004/GA0/223104/N" . "1523-7060" . . . "0"^^ . "0"^^ . "2"^^ . "[F8AE659065C0]" . "Adenosine-deaminase; cytostatic activity; nucleosides; lithiation; reagents; analogs; bases"@en . "Dvo\u0159\u00E1k, Dalimil" . "Tobrman, Tom\u00E1\u0161" . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . . "2"^^ . . . "6-Magnesiated Purines: Preparation and Reaction with Aldehydes" . . "6-Magnesiated Purines: Preparation and Reaction with Aldehydes"@en . "RIV/60461373:22310/03:00008311" . . "Halogen-metal exchange reaction of 9-benzyl-6-iodopurine with iPrMgCl in toluene at -80 degreesC proceeds almost quantitatively. Such a purine-derived Grignard reagent reacts selectively with aldehydes in toluene, giving the corresponding alcohols in 25-62% yield, while other functional groups such as ketones, esters, and nitriles do not react under these conditions. The reaction can be extended to protected 6-iodopurine ribonucleoside." . "23" . . . "3"^^ . "Halogen-metal exchange reaction of 9-benzyl-6-iodopurine with iPrMgCl in toluene at -80 degreesC proceeds almost quantitatively. Such a purine-derived Grignard reagent reacts selectively with aldehydes in toluene, giving the corresponding alcohols in 25-62% yield, while other functional groups such as ketones, esters, and nitriles do not react under these conditions. The reaction can be extended to protected 6-iodopurine ribonucleoside."@en . "Organic Letters" . . "22310" .