. "Karasov\u00E1, Jana" . "Va\u0161ina, Libor" . . . "The evaluation of neuroprotective efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-poisoned rats"@en . . "The evaluation of neuroprotective efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-poisoned rats" . "6" . . . "[1118888C9347]" . "RIV/60162694:G44__/07:00001761" . "621-630" . "Kassa, Ji\u0159\u00ED" . . . "The evaluation of neuroprotective efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-poisoned rats"@en . "27" . . . . "cyclosarin; atropine; K oximes; HI-6; obidoxime; functional observational battery"@en . . "2"^^ . . "Oba nov\u011B vyvinut\u00E9 oximy (K074, K075) stejn\u011B jako obidoxim jsou schopny redukovat cyklosarinem indukovanou akutn\u00ED neurotoxicitu, ale jejich neuroprotektivn\u00ED \u00FA\u010Dinnost je signifikantn\u011B ni\u017E\u0161\u00ED ve srovn\u00E1n\u00ED s oximem HI-6. Proto je oxim HI-6 st\u00E1le nejvhodn\u011Bj\u0161\u00EDm oximem pro antidotn\u00ED terapii akutn\u00ED otravy cyklosarinem vzhledem k jeho neuroprotektivn\u00ED a reaktiva\u010Dn\u00ED \u00FA\u010Dinnosti."@cs . "Journal of Applied Toxicology" . "RIV/60162694:G44__/07:00001761!RIV08-MO0-G44_____" . "3"^^ . . . . "Vyhodnocen\u00ED neuroprotektivn\u00EDho \u00FA\u010Dinku nov\u011B vyvinut\u00FDch oxim\u016F (K074, K075) a v sou\u010Dasnosti dostupn\u00FDch oxim\u016F (obidoxim, HI-6) na potkanech otr\u00E1ven\u00FDch cyklosarinem"@cs . "420761" . . . "Z(MO0FVZ0000501)" . "Both newly developed oximes (K074, K075) as well as obidoxime are also able to counteract cyclosarin-induced acute neurotoxicity but their neuroprotective potency is significantly lower compared to the oxime HI-6. Therefore, the oxime HI-6 is still the most suitable oxime for the antidotal treatment of acute poisonings with cyclosarin due to its neuroprotective as well as reactivating efficacy." . "G44" . "10"^^ . "Vyhodnocen\u00ED neuroprotektivn\u00EDho \u00FA\u010Dinku nov\u011B vyvinut\u00FDch oxim\u016F (K074, K075) a v sou\u010Dasnosti dostupn\u00FDch oxim\u016F (obidoxim, HI-6) na potkanech otr\u00E1ven\u00FDch cyklosarinem"@cs . . "0260-437X" . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "The evaluation of neuroprotective efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-poisoned rats" . "Both newly developed oximes (K074, K075) as well as obidoxime are also able to counteract cyclosarin-induced acute neurotoxicity but their neuroprotective potency is significantly lower compared to the oxime HI-6. Therefore, the oxime HI-6 is still the most suitable oxime for the antidotal treatment of acute poisonings with cyclosarin due to its neuroprotective as well as reactivating efficacy."@en .