"12" . "IrCL1-The haemoglobinolytic cathepsin L of the hard tick, Ixodes ricinus" . . "Blood digestion in the tick gut is based on a multienzyme network comprising acidic peptidases of cysteine and aspartic class. In this work, we provided the detailed biochemical and functional characterization of the cathepsin L named IrCL1 which is involved in the early stage of hemoglobin digestion. Our results suggest that IrCL1 is a promising candidate for development a potential anti-tick vaccine. The article impact was emphasized by the cover page image of the IJP issue."@en . "0020-7519" . "Caffrey, C. R." . "RIV/60077344:_____/11:00367385!RIV12-MSM-60077344" . . "Mare\u0161, Michael" . "205839" . . "Kop\u00E1\u010Dek, Petr" . . . . . "Frantov\u00E1, Helena" . . . . . . "000296110300005" . "Blood digestion in the tick gut is based on a multienzyme network comprising acidic peptidases of cysteine and aspartic class. In this work, we provided the detailed biochemical and functional characterization of the cathepsin L named IrCL1 which is involved in the early stage of hemoglobin digestion. Our results suggest that IrCL1 is a promising candidate for development a potential anti-tick vaccine. The article impact was emphasized by the cover page image of the IJP issue." . "P(GAP207/10/2183), P(GPP502/11/P682), P(IAA600960910), P(LC06009), Z(AV0Z40550506), Z(AV0Z60220518)" . "Franta, Zden\u011Bk" . "IrCL1-The haemoglobinolytic cathepsin L of the hard tick, Ixodes ricinus"@en . "tick gut; hemoglobin digestion; cathepsin L"@en . . "AU - Australsk\u00E9 spole\u010Denstv\u00ED" . "International Journal for Parasitology" . . . "McKerrow, J. H." . . . "RIV/60077344:_____/11:00367385" . "Sojka, Daniel" . "13"^^ . "Craik, C. S." . . . "Talacko, Pavel" . "5"^^ . "10"^^ . . "Horn, Martin" . . "10.1016/j.ijpara.2011.06.006" . . "Schneider, E." . "Srba, Jind\u0159ich" . "IrCL1-The haemoglobinolytic cathepsin L of the hard tick, Ixodes ricinus"@en . . "IrCL1-The haemoglobinolytic cathepsin L of the hard tick, Ixodes ricinus" . . "41" . . "Dvo\u0159\u00E1k, Jan" . . "[AC72A5A1779E]" .