"Structure and function of the native and recombinant mitochondrial MRP1/MRP2 complex from" . . "Struktura a funkce nativn\u00EDho a rekombinantn\u00EDho mitochondri\u00E1ln\u00EDho MRP1/MRP2 komplexu z Trypanosoma brucei"@cs . . . . . . "4"^^ . . . . "Z\u00EDkov\u00E1, Alena" . . . "The mitochondrial RNA-binding proteins (MRP) 1 and 2 play a regulatory role in RNA editing and putative role(s) in RNA processing in Trypanosoma brucei. Here, we report the purification of a high molecular weight protein complex consisting solely of the MRP1 and MRP2 proteins from the mitochondrion of T. brucei. The MRP1/MRP2 complex natively purified from T. brucei and the one reconstituted in E. coli in vivo bind guide (g) RNAs and pre-mRNAs with dissociation constants in the nanomolar range, and efficiently promote annealing of pre-mRNAs with their cognate gRNAs."@en . "Structure and function of the native and recombinant mitochondrial MRP1/MRP2 complex from"@en . . "P(1K04011), P(2B06129), P(GA204/06/1558), P(GP204/04/P191), P(IAA500960705), P(LC07032), S, Z(AV0Z60220518), Z(MSM6007665801)" . "Luke\u0161, Julius" . "8/9" . . . . . "6"^^ . "Mitochondri\u00E1ln\u00ED RNA-v\u00E1\u017E\u00EDc\u00ED proteiny (MRP) 1 a 2 hraj\u00ED regula\u010Dn\u00ED roli p\u0159i editov\u00E1n\u00ED RNA a dal\u0161\u00EDch mo\u017En\u00FDch rol\u00EDch p\u0159i procesov\u00E1n\u00ED u Trypanosoma brucei. V t\u00E9to pr\u00E1ci jsme se zab\u00FDvali \u010Di\u0161t\u011Bn\u00EDm vysokomolekul\u00E1rn\u00EDch proteinov\u00FDch komplex\u016F skl\u00E1daj\u00EDc\u00EDch se pouze z MRP1 a MRP2 protein\u016F z mitochondrie T. brucei. MRP1/MRP2 komplex nativn\u011B vy\u010Di\u0161t\u011Bn\u00FD z T. brucei podobn\u011B jako stejn\u00FD komplex vytvo\u0159en\u00FD v E. coli v\u00E1\u017Ee in vivo guide (g) RNA molekuly, stejn\u011B jako pre-mRNA molekuly s disocia\u010Dn\u00ED konstantou v nanomol\u00E1rn\u00EDm rozsahu. D\u00E1le \u00FA\u010Dinn\u011B zesiluje vazbu pre-mRNAs k jejich p\u0159\u00EDslu\u0161n\u00FDm gRNAs."@cs . . . "12"^^ . "Stuart, K." . . "000257001300003" . . "International Journal for Parasitology" . "frataxin; mitochondrie; trypanosoma; rozsivka; evolu\u010Dn\u00ED konzervovanost; import"@en . "[681197E08D40]" . "Struktura a funkce nativn\u00EDho a rekombinantn\u00EDho mitochondri\u00E1ln\u00EDho MRP1/MRP2 komplexu z Trypanosoma brucei"@cs . "38" . . "AU - Australsk\u00E9 spole\u010Denstv\u00ED" . "Kope\u010Dn\u00E1, Jana" . "Structure and function of the native and recombinant mitochondrial MRP1/MRP2 complex from"@en . . "RIV/60077344:_____/08:00319116!RIV09-GA0-60077344" . "The mitochondrial RNA-binding proteins (MRP) 1 and 2 play a regulatory role in RNA editing and putative role(s) in RNA processing in Trypanosoma brucei. Here, we report the purification of a high molecular weight protein complex consisting solely of the MRP1 and MRP2 proteins from the mitochondrion of T. brucei. The MRP1/MRP2 complex natively purified from T. brucei and the one reconstituted in E. coli in vivo bind guide (g) RNAs and pre-mRNAs with dissociation constants in the nanomolar range, and efficiently promote annealing of pre-mRNAs with their cognate gRNAs." . "RIV/60077344:_____/08:00319116" . . "397811" . . . "0020-7519" . . . . "Trant\u00EDrek, Luk\u00E1\u0161" . "Schumacher, M. A." . "Structure and function of the native and recombinant mitochondrial MRP1/MRP2 complex from" . . .