"Many parasitic Apicomplexa contain an unpigmented chloroplast remnant termed apicoplast, which is a target for malaria treatment. However, no close relative of apicomplexans with a functional photosynthetic plastid has yet been known. Here we describe a newly cultured organism that has ultrastructural features typical of alveolates, is phylogenetically related to apicomplexans, and contains a photosynthetic plastid. The plastid is surrounded by four membranes, is pigmented by chlorophyll a, and uses the codon UGA to encode tryptophan in the psbA gene. This genetic feature has been found only in coccidian apicoplasts and various mitochondria. The UGA-Trp codon and phylogenies of plastid and nuclear ribosomal RNA genes indicate that the organism is the closest known photosynthetic relative to apicomplexan parasites and that its plastid shares an origin with the apicoplasts. The discovery provides a powerful model with which to study the evolution of parasitism in Apicomplexa."@en . "A photosynthetic alveolate closely related to apicomplexan parasites"@en . "Nature" . "14"^^ . . "Davies, N. W." . "P(GA206/06/1439), S, Z(AV0Z60220518)" . "Wright, S. W." . "Oborn\u00EDk, Miroslav" . . "21-02-2008" . "Carter, D. A." . "Green, D. H." . . "Logsdon, J. M." . "RIV/60077344:_____/08:00319108!RIV09-GA0-60077344" . "Hoegh-Guldberg, O." . "A photosynthetic alveolate closely related to apicomplexan parasites"@en . . "A photosynthetic alveolate closely related to apicomplexan parasites" . "5"^^ . "A photosynthetic alveolate closely related to apicomplexan parasites" . . "Moore, R. B." . "Fotosyntetick\u00FD alveol\u00E1t bl\u00EDzce p\u0159\u00EDbuzn\u00FD parazit\u016Fm kmene Apicomplexa"@cs . "4"^^ . "Many parasitic Apicomplexa contain an unpigmented chloroplast remnant termed apicoplast, which is a target for malaria treatment. However, no close relative of apicomplexans with a functional photosynthetic plastid has yet been known. Here we describe a newly cultured organism that has ultrastructural features typical of alveolates, is phylogenetically related to apicomplexans, and contains a photosynthetic plastid. The plastid is surrounded by four membranes, is pigmented by chlorophyll a, and uses the codon UGA to encode tryptophan in the psbA gene. This genetic feature has been found only in coccidian apicoplasts and various mitochondria. The UGA-Trp codon and phylogenies of plastid and nuclear ribosomal RNA genes indicate that the organism is the closest known photosynthetic relative to apicomplexan parasites and that its plastid shares an origin with the apicoplasts. The discovery provides a powerful model with which to study the evolution of parasitism in Apicomplexa." . . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "451" . . "Janou\u0161kovec, Jan" . . "Chrudimsk\u00FD, Tom\u00E1\u0161" . "Fotosyntetick\u00FD alveol\u00E1t bl\u00EDzce p\u0159\u00EDbuzn\u00FD parazit\u016Fm kmene Apicomplexa"@cs . "000253313100041" . . "alveolate; photosynthesis; Chromera velia; evolution; Apicomplexa"@en . . . . . "Bolch, Ch. J. S." . . "Vancov\u00E1, Marie" . "Heimann, K." . "\u0160lapeta, J." . "Mnoho parazitick\u00FDch v\u00FDtrusovc\u016F (Apicomplexa) obsahuje nefotosyntetick\u00FD poz\u016Fstatek plastidu, naz\u00FDvan\u00FD t\u00E9\u017E apikoplast, kter\u00FD je c\u00EDlem pro l\u00E9\u010Dbu mal\u00E1rie. Nicm\u00E9n\u011B, \u017E\u00E1dn\u00FD bl\u00EDzce p\u0159\u00EDbuzn\u00FD v\u00FDtrusovc\u016F s funk\u010Dn\u00EDm fotosyntetick\u00FDm plastidem nebyl dosud pops\u00E1n. Tato pr\u00E1ce popisuje nov\u011B kultivovan\u00FD organismus, kter\u00FD obsahuje ultrastrukturn\u00ED znaky alveol\u00E1t, je fylogeneticky p\u0159\u00EDbuzn\u00FD v\u00FDtrusovc\u016Fm a obsahuje fotosyntetick\u00FD plastid. Tento plastid je obalem \u010Dty\u0159mi membr\u00E1nami, pigmentov\u00E1n chlorofylem a a pou\u017E\u00EDv\u00E1 nekanonick\u00FD k\u00F3d UGA pro tryptofan v psbA genu. Tento genetick\u00FD znak byl dosud nalezen pouze v apikoplastu kokcidi\u00ED a v r\u016Fzn\u00FDch mitochondri\u00EDch. Pou\u017E\u00EDv\u00E1n\u00ED UGA-Trp kodonu a fylogenetick\u00E1 anal\u00FDza na z\u00E1klad\u011B jadern\u00FDch a plastidov\u00FDch gen\u016F ukazuje, \u017Ee nov\u011B objeven\u00FD organismus je nejbli\u017E\u0161\u00ED zn\u00E1m\u00FD fotosyntetick\u00FD p\u0159\u00EDbuzn\u00FD parazit\u016F kmene Apicomplexa a jeho plastid sd\u00EDl\u00ED spole\u010Dn\u00FD p\u016Fvod s apikoplastem. Tento objev p\u0159in\u00E1\u0161\u00ED zcela nov\u00FD model pro studium evoluce parazitismu u prvok\u016F kmene Apicomplexa."@cs . . . . "0028-0836" . . "354394" . "[65D92492938E]" . . . . . "RIV/60077344:_____/08:00319108" . .