"Expertomica metabolite profiling: getting more information from LC-MS using the stochastic systems approach"@en . "Soukup, Ji\u0159\u00ED" . . "[B52D677AB035]" . "4"^^ . "20" . . "Expertomica"@en . "12640" . "Bioinformatics" . "Mass spectrometers are sophisticated,. ne instruments which are essential in a variety applications. However, the data they produce are usually interpreted in a rather primitive way, without considering the accuracy of this data and the potential errors in identifying peaks. Our new approach corrects this situation by dividing the LC-MS output into three components: (i) signature of the analyte, (ii) random noise and (iii) systemic noise. The systemic noise is related to the instrument and to the particular experiment; its characteristics change in time and depend on the analyzed substance. Working with these components allows us to quantify the probability of peak errors and, at the same time, to retrieve some peaks which get lost in the noise when using the existing methods. Our software tool, Expertomica metabolite pro. ling, automatically evaluates the given instrument, detects compounds and calculates the probability of individual peaks. It does not need any artificial user-defined parameters or" . "RIV/60076658:12640/09:00010010" . "Expertomica metabolite profiling: getting more information from LC-MS using the stochastic systems approach" . "Mass spectrometers are sophisticated,. ne instruments which are essential in a variety applications. However, the data they produce are usually interpreted in a rather primitive way, without considering the accuracy of this data and the potential errors in identifying peaks. Our new approach corrects this situation by dividing the LC-MS output into three components: (i) signature of the analyte, (ii) random noise and (iii) systemic noise. The systemic noise is related to the instrument and to the particular experiment; its characteristics change in time and depend on the analyzed substance. Working with these components allows us to quantify the probability of peak errors and, at the same time, to retrieve some peaks which get lost in the noise when using the existing methods. Our software tool, Expertomica metabolite pro. ling, automatically evaluates the given instrument, detects compounds and calculates the probability of individual peaks. It does not need any artificial user-defined parameters or"@en . "3"^^ . . "25" . "4"^^ . . "Van\u011Bk, Jan" . . "RIV/60076658:12640/09:00010010!RIV10-MSM-12640___" . "Urban, Jan" . . "1367-4803" . . "\u0160tys, Dalibor" . . . "Expertomica metabolite profiling: getting more information from LC-MS using the stochastic systems approach" . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . . . . . "000270685200030" . "Expertomica metabolite profiling: getting more information from LC-MS using the stochastic systems approach"@en . . . "S, Z(MSM6007665808)" . . "314369" .