. . . "369186" . . . "x" . . "127" . "Genus Nostoc - a source of novel trypsin inhibitors"@en . "0003-9136" . "4"^^ . "In extracts from fifty newly-isolated strains of the genus Nostoc, numerous new molecules showing a capacity for protease inhibition were identified. The production conditions of the most active molecule, found in the Nostoc sp., strain LUKE\u0160OV\u00C1 30/93, were studied in detail and the optimal physiological parameters (growth phase, light intensity and culture temperature) examined. The highest active compound concentration was usually found 3 days after inoculation in cultures grown under optimum conditions (light intensity 70 W.m-2 and temperature 25\u00B0C). Similar observations seemed to be found for the other strains examined in the study. As far as the trypsin-inhibiting secondary metabolites is concerned, we may thus conclude that we have found no dependency on cell growth phase, light intensity or temperature otheer than leading to optimum growth conditions. We propose that the production of the trypsin inhibitor is coincident with conditions under which the colony of the microorganism mostly prospers" . . "In extracts from fifty newly-isolated strains of the genus Nostoc, numerous new molecules showing a capacity for protease inhibition were identified. The production conditions of the most active molecule, found in the Nostoc sp., strain LUKE\u0160OV\u00C1 30/93, were studied in detail and the optimal physiological parameters (growth phase, light intensity and culture temperature) examined. The highest active compound concentration was usually found 3 days after inoculation in cultures grown under optimum conditions (light intensity 70 W.m-2 and temperature 25\u00B0C). Similar observations seemed to be found for the other strains examined in the study. As far as the trypsin-inhibiting secondary metabolites is concerned, we may thus conclude that we have found no dependency on cell growth phase, light intensity or temperature otheer than leading to optimum growth conditions. We propose that the production of the trypsin inhibitor is coincident with conditions under which the colony of the microorganism mostly prospers"@en . . . "Archiv f\u00FCr Hydrobiologie" . . . "Rod Nostoc jako zdroj nov\u00FDch inhibitor\u016F trypsinu."@cs . "Cyanobacteria; Nostoc; trypsin inhibitors; LC/MS; peptides"@en . . "2"^^ . "\u0160tys, Dalibor" . . "Luke\u0161ov\u00E1, Alena" . . "12640" . "Genus Nostoc - a source of novel trypsin inhibitors" . . "Rod Nostoc jako zdroj nov\u00FDch inhibitor\u016F trypsinu."@cs . "P(ME 874), V, Z(AV0Z50200510), Z(AV0Z60660521)" . "DE - Spolkov\u00E1 republika N\u011Bmecko" . "Kopeck\u00FD, Ji\u0159\u00ED" . "V extraktech p\u0159ipraven\u00FDch z 50 nov\u011B izolovan\u00FDch kmen\u016F sinic rodu Nostoc bylo identifikov\u00E1no n\u011Bkolik l\u00E1tek vykazuj\u00EDc\u00EDch silnou inhibi\u010Dn\u00ED aktivitu v\u016F\u010Di enzymu trypsinu. Detailn\u00ED produk\u010Dn\u00ED podm\u00EDnky pro l\u00E1tku nalezenou v kmeni Nostoc sp., strain LUKE\u0160OV\u00C1 30/93 byly studov\u00E1ny a optim\u00E1ln\u00ED fyziologick\u00E9 parametry (vliv r\u016Fstov\u00E9 f\u00E1ze, intenzity sv\u011Btla a kultiva\u010Dn\u00ED teploty) byly pro tento kmen stanoveny."@cs . "Genus Nostoc - a source of novel trypsin inhibitors" . "Genus Nostoc - a source of novel trypsin inhibitors"@en . . . . . "10"^^ . . "RIV/60076658:12640/08:00009971!RIV09-MSM-12640___" . "RIV/60076658:12640/08:00009971" . "Dr\u00E1palov\u00E1, Petra" . "[BD3708292772]" . . .