"11" . "0024-4201" . "Z(MSM6007665809)" . "V pr\u00E1ci byl sledov\u00E1n efekt p\u0159\u00EDdavku sm\u011Bsi sezaminu a episezaminu do ryb\u00EDch krmiv obsahuj\u00EDc\u00EDch rostlinn\u00E9 oleje s r\u016Fzn\u00FDm slo\u017Een\u00EDm mastn\u00FDch kyselin. Sezamin/episezamin (d\u00E1le jen sezamin) byl p\u0159id\u00E1n v koncentraci 0.58 g/100 g krmiva. Oleje pou\u017Eit\u00E9 v krmivu byly sm\u011Bs\u00ED ln\u011Bn\u00E9ho a slune\u010Dnicov\u00E9ho oleje (6:4, obj.) nebo 100% ln\u011Bn\u00FD olej. P\u0159\u00EDdavek sezaminu zp\u016Fsobil 37% zv\u00FD\u0161en\u00ED obsahu dokosahexaenov\u00E9 kyseliny (DHA) ve fosfolipidov\u00E9 a triacylglycerolov\u00E9 frakci b\u00EDl\u00E9 svaloviny, p\u0159i\u010Dem\u017E mastn\u00E9 kyseliny v \u010Derven\u00E9 svalovin\u011B a j\u00E1trech nebyly ovlivn\u011Bny. Exprese PPAR byla v\u00FDznamn\u011B sn\u00ED\u017Eena (P0.05) v j\u00E1trech ryb krmen\u00FDch krmivem obsahuj\u00EDc\u00EDm sezamin a sm\u011Bs\u00ED olej\u016F. Sezamin a episezamin byl detekov\u00E1n v j\u00E1trech a svalovin\u011B ryb kter\u00FDm byl sezamin pod\u00E1v\u00E1n. V j\u00E1trech ryb krmen\u00FDch sezaminem byly zji\u0161t\u011Bny zv\u00FD\u0161en\u00E9 hodnoty obsahu cytochromu P450 (CYP) a zv\u00FD\u0161en\u00E1 aktivita enzymu EROD, nasv\u011Bd\u010Duj\u00EDc\u00ED indukci CYP1A v t\u00E9to tk\u00E1ni. Ve shrnut\u00ED m\u016F\u017Eeme \u0159\u00EDct, \u017Ee p\u0159\u00EDdavek sezaminu v krmivu zv\u00FD\u0161il pom\u011Br DHA v b\u00EDl\u00E9 svalovin\u011B ryb."@cs . "Gj\u00F8en, T." . . "Sesamin Supplementation Increases White Muscle Docosahexaenoic Acid (DHA) Levels in Rainbow Trout (Oncorhynchus mykiss) Fed High Alpha-Linolenic Acid (ALA) Containing Vegetable Oil: Metabolic Actions" . "P\u0159\u00EDdavek sezaminu zvy\u0161uje hladinu dokosahexaenov\u00E9 kyseliny (DHA) v b\u00EDl\u00E9 svalovin\u011B pstruha duhov\u00E9ho (Oncorhynchus mykiss) krmen\u00E9ho dietou obsahuj\u00EDc\u00ED rostlinn\u00FD olej s vysok\u00FDm obsahem alfa-linolenov\u00E9 kyseliny (ALA): Metabolick\u00E9 procesy"@cs . "000260526200002" . "Moazzami, A." . . . "\u017Dl\u00E1bek, Vladim\u00EDr" . . . . "Trattner, Sofia" . . "2"^^ . "Sesamin Supplementation Increases White Muscle Docosahexaenoic Acid (DHA) Levels in Rainbow Trout (Oncorhynchus mykiss) Fed High Alpha-Linolenic Acid (ALA) Containing Vegetable Oil: Metabolic Actions"@en . . . "RIV/60076658:12610/08:00008923" . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "9"^^ . . "Kamal-Eldin, A." . "9"^^ . "P\u0159\u00EDdavek sezaminu zvy\u0161uje hladinu dokosahexaenov\u00E9 kyseliny (DHA) v b\u00EDl\u00E9 svalovin\u011B pstruha duhov\u00E9ho (Oncorhynchus mykiss) krmen\u00E9ho dietou obsahuj\u00EDc\u00ED rostlinn\u00FD olej s vysok\u00FDm obsahem alfa-linolenov\u00E9 kyseliny (ALA): Metabolick\u00E9 procesy"@cs . "Larsson, P." . "[A4C54A280947]" . . "RIV/60076658:12610/08:00008923!RIV09-MSM-12610___" . . . "Pickov\u00E1, Jana" . "Brannaas, E." . "Sesamin; episesamin; DHA; EPA; fish; PPARs; cytochrome P450"@en . "The effects of including an equi-mixture of sesamin and episesamin in fish diets based on vegetable oils of different fatty acid composition were examined. Sesamin/episesamin (hereafter named sesamin) was included at 0.58 g/100 g diet. The oil used in the feed was either a mixture of linseed and sunflower oils (6:4, by vol) or 100% linseed oil. Addition of sesamin increased the percentages of docosahexaenoic acid (DHA) in white muscle phospholipid and triacylglycerol fraction by up to 37% but the fatty acids in red muscle and liver were not affected. The expression of the peroxisome proliferator-activated receptor PPARa was significantly down regulated in the liver of the fish fed sesamin and mixed oil diet (P0.05). Sesamin and episesamin were detected in liver and muscle tissues of the fish that had been fed sesamin. Fish fed sesamin had elevated levels of total cytochrome P450 (CYP) enzymes and EROD activity in the liver, indicating an induction of CYP1A in this tissue. Our conclusion was that suppl" . . "394514" . . "Ruyter, B." . "Lipids" . . "12610" . . "Sesamin Supplementation Increases White Muscle Docosahexaenoic Acid (DHA) Levels in Rainbow Trout (Oncorhynchus mykiss) Fed High Alpha-Linolenic Acid (ALA) Containing Vegetable Oil: Metabolic Actions"@en . "Sesamin Supplementation Increases White Muscle Docosahexaenoic Acid (DHA) Levels in Rainbow Trout (Oncorhynchus mykiss) Fed High Alpha-Linolenic Acid (ALA) Containing Vegetable Oil: Metabolic Actions" . . "43" . "The effects of including an equi-mixture of sesamin and episesamin in fish diets based on vegetable oils of different fatty acid composition were examined. Sesamin/episesamin (hereafter named sesamin) was included at 0.58 g/100 g diet. The oil used in the feed was either a mixture of linseed and sunflower oils (6:4, by vol) or 100% linseed oil. Addition of sesamin increased the percentages of docosahexaenoic acid (DHA) in white muscle phospholipid and triacylglycerol fraction by up to 37% but the fatty acids in red muscle and liver were not affected. The expression of the peroxisome proliferator-activated receptor PPARa was significantly down regulated in the liver of the fish fed sesamin and mixed oil diet (P0.05). Sesamin and episesamin were detected in liver and muscle tissues of the fish that had been fed sesamin. Fish fed sesamin had elevated levels of total cytochrome P450 (CYP) enzymes and EROD activity in the liver, indicating an induction of CYP1A in this tissue. Our conclusion was that suppl"@en . . .