"Vyu\u017Eit\u00ED biomarker\u016F stanoven\u00FDch u jelce tlou\u0161t\u011B (Leuciscus cephalus L.) pro hodnocen\u00ED kontaminace \u0159ek Labe a Vltava v \u010CR"@cs . "In territory of the Czech Republic, the middle reach of the Elbe river and the lower reach of the Vltava river downstream Prague are the most polluted aquatic ecosystems. Heavy metals and organic coumpounds have been deposited here. They accumulate in the food chain and negatively affect the aquatic biota. The chub (Leuciscus cephalus L.) was selected as a suitable bioindicator for the field study. Blood plasma and tissue samples were collected from wild chub (Leuciscus cephalus L.) from 9 localities of the Elbe and Vltava rivers and from 1 locality of the Blanice river (control locality), Czech Republic, in 2003. Samples of blood plasma were analyzed for the yolk protein precursor vitellogenin (VTG), a biomarker for estrogen exposure, and for sex steroid - 11 - ketotestosterone (11-KT) to investigate for evidence of endocrine modulation. Liver samples were analyzed for EROD activity, biomarker of aquatic environment contamination by a large spectrum of industrial pollutants. Bile samples were anal" . . . . "12610" . "The application of biomarkers detected in chub (Leuciscus cephalus L.) to evaluate contamination of the Elbe and Vltava Rivers, Czech Republic"@en . . "UFZ-Bericht" . "4"^^ . "0948-9452" . . "In territory of the Czech Republic, the middle reach of the Elbe river and the lower reach of the Vltava river downstream Prague are the most polluted aquatic ecosystems. Heavy metals and organic coumpounds have been deposited here. They accumulate in the food chain and negatively affect the aquatic biota. The chub (Leuciscus cephalus L.) was selected as a suitable bioindicator for the field study. Blood plasma and tissue samples were collected from wild chub (Leuciscus cephalus L.) from 9 localities of the Elbe and Vltava rivers and from 1 locality of the Blanice river (control locality), Czech Republic, in 2003. Samples of blood plasma were analyzed for the yolk protein precursor vitellogenin (VTG), a biomarker for estrogen exposure, and for sex steroid - 11 - ketotestosterone (11-KT) to investigate for evidence of endocrine modulation. Liver samples were analyzed for EROD activity, biomarker of aquatic environment contamination by a large spectrum of industrial pollutants. Bile samples were anal"@en . . . . "[CCE14AC717D6]" . . "RIV/60076658:12610/04:00005815" . "6"^^ . "2"^^ . "Leipzig-Halle" . "\u017Dl\u00E1bek, Vladim\u00EDr" . . "Leipzig-Halle" . "RIV/60076658:12610/04:00005815!RIV/2005/MSM/126105/N" . "Kol\u00E1\u0159ov\u00E1, Jitka" . . "Rand\u00E1k, Tom\u00E1\u0161" . . "\u0160irok\u00E1, Z." . . . "St\u0159edn\u00ED tok Labe a doln\u00ED tok Vltavy je mo\u017Eno pova\u017Eovat za nejv\u00EDce zat\u00ED\u017Een\u00E9 vodn\u00ED ekosyst\u00E9my cizorod\u00FDmi l\u00E1tkami na \u00FAzem\u00ED \u010Cesk\u00E9 republiky. V\u00FDznamn\u00FDmi kontaminanty jsou toxick\u00E9 kovy a perzistentn\u00ED organick\u00E9 slou\u010Deniny. Kumuluj\u00ED se v potravn\u00EDm \u0159et\u011Bzci a negativn\u011B ovli\u0148uj\u00ED vodn\u00ED organismy. Jelec tlou\u0161\u0165 (Leuciscus cephalus L.) byl vybr\u00E1n jako nejvhodn\u011Bj\u0161\u00ED bioindik\u00E1tor pro studium \u00FA\u010Dink\u016F cizorod\u00FDch l\u00E1tek p\u0159\u00EDtomn\u00FDch ve vod\u011B na ryb\u00ED organismus. V roce 2003 byly na dev\u00EDti lokalit\u00E1ch \u0159ek Labe a Vltavy na jedn\u00E9 (kontroln\u00ED) lokalit\u011B \u0159eky Blanice odebr\u00E1ny od voln\u011B \u017Eij\u00EDc\u00EDch jelc\u016F tlou\u0161\u0165\u016F vzorky krevn\u00ED plazmy a tk\u00E1n\u00ED. Vzorky krevn\u00ED plazmy byly analyzov\u00E1ny na obsah vitellogeninu (VTG) a na obsah steroidn\u00EDho hormonu 11-ketotestosteronu (11-KT). Ve vzorc\u00EDch jater byla zji\u0161\u0165ov\u00E1na \u00FArove\u0148 aktivity EROD. Vzorky \u017Elu\u010Di byly analyzov\u00E1ny na obsah 1-hydroxypyrenu (1-OHPY). Vzorky svaloviny ryb byly analyzov\u00E1ny na obsah toxick\u00FDch kov\u016F (Hg, Cd, Pb, As), perzistentn\u00EDch organochlorovan\u00FDch polutant\u016F (PCB, DDT, HCH, HCB, OCS) a alky"@cs . . . . "Z(MSM 126100003)" . . "271-272" . "jelec tlou\u0161\u0165 (Leuciscus cephalus);ryba;biochemick\u00FD marker;toxick\u00E9 kovy;persistentn\u00ED organochlorovan\u00E9 polutanty;alkylfenoly"@en . "Svobodov\u00E1, Zde\u0148ka" . "11th Magdeburg seminar on waters in central Europe: Assessment, Protection, Management" . "The application of biomarkers detected in chub (Leuciscus cephalus L.) to evaluate contamination of the Elbe and Vltava Rivers, Czech Republic" . . "Vyu\u017Eit\u00ED biomarker\u016F stanoven\u00FDch u jelce tlou\u0161t\u011B (Leuciscus cephalus L.) pro hodnocen\u00ED kontaminace \u0159ek Labe a Vltava v \u010CR"@cs . . . . "2004-10-18+02:00"^^ . "555051" . "The application of biomarkers detected in chub (Leuciscus cephalus L.) to evaluate contamination of the Elbe and Vltava Rivers, Czech Republic" . "The application of biomarkers detected in chub (Leuciscus cephalus L.) to evaluate contamination of the Elbe and Vltava Rivers, Czech Republic"@en . "Haj\u0161lov\u00E1, J." .