. . "3"^^ . "12520" . "High performance liquid chromatography (HPLC) in tandem with mass spectrometry (MS) is widely used in chemical and biochemical analysis of the content of measured samples, especially in so-called omics science. Currently, there are methods for processing and analyzing the measured data sets from proteomics as well as metabolomics. However, only some of the problems of processing and analyzing tasks have been compensated for, and even in these cases, they have only been considered independently. Therefore, the current state of data handling is studied. This review describes the currently available methods and techniques commonly used in HPLC-MS for processing and analysis. All the main types of processing and most popular methods are mentioned. However, any overview will fail to be exhaustive. Therefore, some additional literature that goes into further detail is recommended. The review itself reveals some of the important shortcomings of the current state of the art. A list of relevant subtopics relating to different research focuses is provided in the conclusion."@en . . "\u0160tys, Dalibor" . "3"^^ . . "Van\u011Bk, Jan" . "Current State of HPLC-MS Data Processing and Analysis in Proteomics and Metabolomics" . . . . . . "RIV/60076658:12520/12:43884034" . "Current State of HPLC-MS Data Processing and Analysis in Proteomics and Metabolomics"@en . . "[2343E46EC5D7]" . "P(ED2.1.00/01.0024), Z(MSM6007665808)" . . "RIV/60076658:12520/12:43884034!RIV13-MSM-12520___" . "129275" . "Urban, Jan" . . . . "2" . . "10.2174/157016412800786248" . "000305654000002" . "1570-1646" . "CURRENT PROTEOMICS" . "9" . "14"^^ . . . "Current State of HPLC-MS Data Processing and Analysis in Proteomics and Metabolomics" . . . "AE - St\u00E1t Spojen\u00E9 arabsk\u00E9 emir\u00E1ty" . "Current State of HPLC-MS Data Processing and Analysis in Proteomics and Metabolomics"@en . "High performance liquid chromatography (HPLC) in tandem with mass spectrometry (MS) is widely used in chemical and biochemical analysis of the content of measured samples, especially in so-called omics science. Currently, there are methods for processing and analyzing the measured data sets from proteomics as well as metabolomics. However, only some of the problems of processing and analyzing tasks have been compensated for, and even in these cases, they have only been considered independently. Therefore, the current state of data handling is studied. This review describes the currently available methods and techniques commonly used in HPLC-MS for processing and analysis. All the main types of processing and most popular methods are mentioned. However, any overview will fail to be exhaustive. Therefore, some additional literature that goes into further detail is recommended. The review itself reveals some of the important shortcomings of the current state of the art. A list of relevant subtopics relating to different research focuses is provided in the conclusion." . "time alignment; mass spectrometry; liquid chromatography; Feature detection"@en . . .