. "Ber\u00E1nek, Ladislav" . . . "CZ - \u010Cesk\u00E1 republika" . . . "Kantorov\u00E1, Eva" . "Racek, Jaroslav" . "Journal of Applied Biomedicine" . "Changes in selected parameters of the antioxidant system in radiation damage to the organism"@en . "antioxidant system; blood plasma; ionizing radiation"@en . . "Havr\u00E1nkov\u00E1, Renata" . . . "\u0160iffnerov\u00E1, Hana" . "RIV/60076658:12110/08:00009956!RIV09-MZ0-12110___" . . "4"^^ . "Changes in selected parameters of the antioxidant system in radiation damage to the organism"@en . "Changes in selected parameters of the antioxidant system in radiation damage to the organism" . . "Navr\u00E1til, Leo\u0161" . "12110" . . "C\u00EDlem pr\u00E1ce byla studium oxida\u010Dn\u011B-reduk\u010Dn\u00EDho syst\u00E9mu organizmu po\u0161kozen\u00E9ho ionizuj\u00EDc\u00EDm z\u00E1\u0159en\u00EDm. Byla sledov\u00E1na aktivita superoxiddismut\u00E1zy v \u010Derven\u00FDch krvink\u00E1ch, koncentrace glutathionu v \u010Derven\u00FDch krvink\u00E1ch, aktivita glutathion peroxid\u00E1zy v celkov\u00E9 krvi, koncentrace malondialdehydu v krevn\u00ED plazm\u011B a antioxida\u010Dn\u00ED kapacita krevn\u00ED plazmy. Uveden\u00E9 parametry byly sledovan\u00E9 ve \u010Dty\u0159ech skupin\u00E1ch (u nemocn\u00FDch po radioterapii, u dobrovoln\u00FDch d\u00E1rc\u016F, jejich\u017E krev byla oz\u00E1\u0159ena po odb\u011Bru in vitro, u zam\u011Bstnanc\u016F atomov\u00E9 elektr\u00E1rny a skupiny zdrav\u00FDch osob). Statisticky v\u00FDznamn\u00FD pokles aktivity GSHPx jsme nam\u011B\u0159ili u pacient\u016F po radioterapii a u zam\u011Bstnanc\u016F atomov\u00E9 elektr\u00E1rny. V\u00FDsledky zpracov\u00E1n\u00ED dat z\u00EDskan\u00FDch metodou mnohorozm\u011Brn\u00E9 anal\u00FDzy rozptylu dokumentuj\u00ED, \u017Ee dynamika zm\u011Bn je porovnateln\u00E1 ve skupin\u011B pacient\u016F po radioterapii a zam\u011Bstnanc\u016F atomov\u00E9 elektr\u00E1rny na stran\u011B jedn\u00E9 a v kontroln\u00ED skupin\u011B a skupin\u011B zdrav\u00FDch dobrovoln\u00EDk\u016F, jejich\u017E krev byla oz\u00E1\u0159ena in vitro, na stran\u011B druh\u00E9. Studi\u00ED jsme prok\u00E1zali zm\u011Bny ve vy"@cs . "7"^^ . "1214-021X" . . "RIV/60076658:12110/08:00009956" . "Zm\u011Bny u vybran\u00FDch parametr\u016F antioxida\u010Dn\u00EDho syst\u00E9mu po po\u0161kozen\u00ED organizmu ionizuj\u00EDc\u00EDm z\u00E1\u0159en\u00EDm"@cs . . "Zm\u011Bny u vybran\u00FDch parametr\u016F antioxida\u010Dn\u00EDho syst\u00E9mu po po\u0161kozen\u00ED organizmu ionizuj\u00EDc\u00EDm z\u00E1\u0159en\u00EDm"@cs . "The target of the present work was a study of the oxidation-reduction system of the organism damaged with ionizing radiation. The parameters chosen for examination were: the superoxide dismutase activity in erythrocytes, the concentration of reduced glutathione in erythrocytes, the activity of glutathione peroxidase in the total blood, the concentration of malondialdehyde in the blood plasma, and the antioxidant capacity of blood plasma. These parameters were monitored in four groups (patients after radiotherapy, volunteers whose blood was submitted to in vitro irradiation, employees of a nuclear power plant, and a group of healthy persons). A statistically significant decrease in the GSHPx activity was measured in patients after radiotherapy and in employees of the nuclear power plant. Results of processing the data obtained by the method of multidimensional analysis of variance suggest that the dynamics of the changes is comparable in the group of patients after radiotherapy and employees of the nuc"@en . "7"^^ . "Freitinger Skalick\u00E1, Zuzana" . . . "6" . . . "Changes in selected parameters of the antioxidant system in radiation damage to the organism" . "The target of the present work was a study of the oxidation-reduction system of the organism damaged with ionizing radiation. The parameters chosen for examination were: the superoxide dismutase activity in erythrocytes, the concentration of reduced glutathione in erythrocytes, the activity of glutathione peroxidase in the total blood, the concentration of malondialdehyde in the blood plasma, and the antioxidant capacity of blood plasma. These parameters were monitored in four groups (patients after radiotherapy, volunteers whose blood was submitted to in vitro irradiation, employees of a nuclear power plant, and a group of healthy persons). A statistically significant decrease in the GSHPx activity was measured in patients after radiotherapy and in employees of the nuclear power plant. Results of processing the data obtained by the method of multidimensional analysis of variance suggest that the dynamics of the changes is comparable in the group of patients after radiotherapy and employees of the nuc" . "4" . . . "359463" . "P(NJ7461), V" . "[864E9A49BD40]" .