"C\u00EDlem t\u00E9to pr\u00E1ce typu review je stru\u010Dn\u011B sezn\u00E1mit s histori\u00ED a p\u0159edev\u0161\u00EDm sou\u010Dasnost\u00ED chirurgick\u00FDch metod l\u00E9\u010Dby degenerativn\u00EDch onemocn\u011Bn\u00ED p\u00E1te\u0159e pomoc\u00ED implant\u00E1t\u016F, mezi kter\u00FDmi zauj\u00EDm\u00E1 v\u00FDrazn\u00E9 m\u00EDsto pr\u00E1v\u011B n\u00E1hrada disku. D\u00E1le je c\u00EDlem informovat o trendech a p\u0159edpokladech budouc\u00EDho v\u00FDvoje. P\u0159esto\u017Ee n\u011Bkter\u00E9 v sou\u010Dasnosti pou\u017E\u00EDvan\u00E9 n\u00E1hrady disku byly vyvinuty i p\u0159ed 20ti lety, st\u00E1le prob\u00EDh\u00E1 jejich testov\u00E1n\u00ED a optimalizace s nejednozna\u010Dn\u00FDmi v\u00FDsledky p\u0159\u00EDnosu oproti klasick\u00FDm metod\u00E1m f\u016Fze. Jak\u00E9si zaost\u00E1v\u00E1n\u00ED nap\u0159. za n\u00E1hradami velk\u00FDch kloub\u016F, kter\u00E9 se ji\u017E pova\u017Euj\u00ED za \u00FAsp\u011B\u0161n\u011B zvl\u00E1dnut\u00E9 nen\u00ED zp\u016Fsobeno nedostatkem invence v\u00FDvojov\u00FDch t\u00FDm\u016F. Tento stav je zp\u016Fsoben komplexnost\u00ED probl\u00E9mu, kdy je p\u016Fvod bolesti ve slo\u017Eit\u00E9m syst\u00E9mu p\u00E1te\u0159e i s vyu\u017Eit\u00EDm modern\u00EDch metod \u010Dasto pouze odhadov\u00E1n. Za t\u011Bchto podm\u00EDnek je pak volba efektivn\u00ED l\u00E9\u010Dby zna\u010Dn\u011B zt\u00ED\u017Eena. Nejen proto, \u017Ee znalost klinick\u00FDch v\u00FDsledk\u016F a p\u0159\u00ED\u010Din selh\u00E1n\u00ED soudob\u00FDch koncepc\u00ED implant\u00E1t\u016F je d\u016Fle\u017Eit\u00E1 pro jejich dal\u0161\u00ED vylep\u0161en\u00ED a tvorbu koncepc\u00ED nov\u00FDch, je zd\u016Fraz\u0148ov\u00E1na pot\u0159eba proveden\u00ED rozs\u00E1hl\u00FDch a dlouhodob\u00FDch studi\u00ED s jednotn\u00FDmi metodikami a definicemi. V budoucnu je d\u00E1le d\u016Fle\u017Eit\u00E9 soust\u0159edit se tak\u00E9 na v\u00FDzkum p\u0159\u00ED\u010Din bolesti zad a na v\u00FDvoj pokro\u010Dil\u00FDch metod l\u00E9\u010Dby degenerativn\u00EDch onemocn\u011Bn\u00ED, jak\u00FDmi jsou nap\u0159. bun\u011B\u010Dn\u00E9, nebo genov\u00E9 terapie." . . "INTERVERTEBRAL DISC REPLACEMENT \u2013 THE PAST, PRESENT AND FUTURE"@en . "Praha" . . . . "Praha" . "Intervertebral disc replacement; disc arthroplasty; past; present; future; trends; outcomes"@en . "[399FE6AC6D61]" . "1"^^ . . "Pohybov\u00E9 aktivity ve v\u011Bd\u011B a praxi" . "P(TA01010860)" . . . "Univerzita Karlova v Praze. Nakladatelstv\u00ED Karolinum" . "The aim of this review is to provide brief information on history and specially on the present-day surgical methods, which are used to treat degenerative disorders of the spine using the intervertebral disc replacement \u2013 as it is one of the most distinctive implant conceptions. Information on the trends and future evolution is also given. Although some of the current disc replacements were developed nearly 20 years ago, its testing and optimization is still runing and outcomes, superior to conventional fusion methods are unproven. This lagging behind the successfully used large joint replacements is not in the lack of the ingenuity. The origin is more likely in the complexity of the issue, when the source of pain is frequently more guessed, than determined in the sophisticated system of the spine independently on modern diagnostic abilities. Upon these conditions, the choice of the efficient treatment is very difficult. Because the knowledge of the current concepts outcomes and causes of failure is important for further advancements - the need of wide and long-term studies with uniform methods and definitions is accented. In the future, there is also important to focus on the true origin of pain and on the advanced methods of the treatment like cell and gene terapy development."@en . "N\u00C1HRADA MEZIOBRATLOV\u00C9HO DISKU \u2013 HISTORIE, SOU\u010CASNOST A BUDOUCNOST" . . . . . "RIV/45145466:_____/14:#8600006!RIV15-TA0-45145466" . "RIV/45145466:_____/14:#8600006" . . . . "10"^^ . "http://www.cupress.cuni.cz/ink2_stat/index.jsp?include=podrobnosti&id=12259" . . . . "INTERVERTEBRAL DISC REPLACEMENT \u2013 THE PAST, PRESENT AND FUTURE"@en . "N\u00C1HRADA MEZIOBRATLOV\u00C9HO DISKU \u2013 HISTORIE, SOU\u010CASNOST A BUDOUCNOST" . "2013-01-01+01:00"^^ . "Bodl\u00E1k, Daniel" . "N\u00C1HRADA MEZIOBRATLOV\u00C9HO DISKU \u2013 HISTORIE, SOU\u010CASNOST A BUDOUCNOST"@cs . "31414" . . . "978-80-246-2654-3" . "N\u00C1HRADA MEZIOBRATLOV\u00C9HO DISKU \u2013 HISTORIE, SOU\u010CASNOST A BUDOUCNOST"@cs . "C\u00EDlem t\u00E9to pr\u00E1ce typu review je stru\u010Dn\u011B sezn\u00E1mit s histori\u00ED a p\u0159edev\u0161\u00EDm sou\u010Dasnost\u00ED chirurgick\u00FDch metod l\u00E9\u010Dby degenerativn\u00EDch onemocn\u011Bn\u00ED p\u00E1te\u0159e pomoc\u00ED implant\u00E1t\u016F, mezi kter\u00FDmi zauj\u00EDm\u00E1 v\u00FDrazn\u00E9 m\u00EDsto pr\u00E1v\u011B n\u00E1hrada disku. D\u00E1le je c\u00EDlem informovat o trendech a p\u0159edpokladech budouc\u00EDho v\u00FDvoje. P\u0159esto\u017Ee n\u011Bkter\u00E9 v sou\u010Dasnosti pou\u017E\u00EDvan\u00E9 n\u00E1hrady disku byly vyvinuty i p\u0159ed 20ti lety, st\u00E1le prob\u00EDh\u00E1 jejich testov\u00E1n\u00ED a optimalizace s nejednozna\u010Dn\u00FDmi v\u00FDsledky p\u0159\u00EDnosu oproti klasick\u00FDm metod\u00E1m f\u016Fze. Jak\u00E9si zaost\u00E1v\u00E1n\u00ED nap\u0159. za n\u00E1hradami velk\u00FDch kloub\u016F, kter\u00E9 se ji\u017E pova\u017Euj\u00ED za \u00FAsp\u011B\u0161n\u011B zvl\u00E1dnut\u00E9 nen\u00ED zp\u016Fsobeno nedostatkem invence v\u00FDvojov\u00FDch t\u00FDm\u016F. Tento stav je zp\u016Fsoben komplexnost\u00ED probl\u00E9mu, kdy je p\u016Fvod bolesti ve slo\u017Eit\u00E9m syst\u00E9mu p\u00E1te\u0159e i s vyu\u017Eit\u00EDm modern\u00EDch metod \u010Dasto pouze odhadov\u00E1n. Za t\u011Bchto podm\u00EDnek je pak volba efektivn\u00ED l\u00E9\u010Dby zna\u010Dn\u011B zt\u00ED\u017Eena. Nejen proto, \u017Ee znalost klinick\u00FDch v\u00FDsledk\u016F a p\u0159\u00ED\u010Din selh\u00E1n\u00ED soudob\u00FDch koncepc\u00ED implant\u00E1t\u016F je d\u016Fle\u017Eit\u00E1 pro jejich dal\u0161\u00ED vylep\u0161en\u00ED a tvorbu koncepc\u00ED nov\u00FDch, je zd\u016Fraz\u0148ov\u00E1na pot\u0159eba proveden\u00ED rozs\u00E1hl\u00FDch a dlouhodob\u00FDch studi\u00ED s jednotn\u00FDmi metodikami a definicemi. V budoucnu je d\u00E1le d\u016Fle\u017Eit\u00E9 soust\u0159edit se tak\u00E9 na v\u00FDzkum p\u0159\u00ED\u010Din bolesti zad a na v\u00FDvoj pokro\u010Dil\u00FDch metod l\u00E9\u010Dby degenerativn\u00EDch onemocn\u011Bn\u00ED, jak\u00FDmi jsou nap\u0159. bun\u011B\u010Dn\u00E9, nebo genov\u00E9 terapie."@cs . "1"^^ . .