. . "XX. Biologick\u00E9 dny : Kmenov\u00E9 bu\u0148ky \u2013 od regenerativn\u00ED medic\u00EDny k n\u00E1dorov\u00E9 biologii" . . "2011-01-01+01:00"^^ . "P(FR-TI1/378)" . "The cell damage and regeneration in the immature brain and glioma cultures irradiated by epithermal neutron beam of the LVR-15 nuclear reactor in \u0158e\u017E"@en . "Marek, Milan" . "RIV/26722445:_____/11:#0000651" . . "Boron-Neutron-Capture-Therapy"@en . . . . "189372" . "Burian, Ji\u0159\u00ED" . "Interaction of epithermal neutrons with boron-10 (10B) leads to a damage of tumor tissue conferred (circumscribed) even soliatary cells. The nuclear reactors used for tumor therapy (Boron-Neutron-Capture-Therapy, BNCT) require individual tuning and monitoring by physical and biological methods. Here, were report effects of epithermal beam of the LVR-15 in \u0158e\u017E (7.8x 108n/cm2, 9 MW, 16.1 cGy/min) on the immature rat brain and C6 glioma culture, the model developed by us for this purpose (Mares et al. 1997, Burian et al. Kagawa). Irradiation of animals for 4 to 7 minutes induced the dose- and the cell differentiation degree- dependent apoptosis-like death in the cerebellum and forebrain, exceeding 2.1 times a gamma radiation equivalent. 3 days later, a dose inverse regeneration was evident in the cerebellum. In cultures irradiated for 30 to 45 min, the cells slowed-down cycling and cell death reaching a peak value at 72 to 96 h."@en . . "[E11FCC4EE343]" . "The cell damage and regeneration in the immature brain and glioma cultures irradiated by epithermal neutron beam of the LVR-15 nuclear reactor in \u0158e\u017E" . . . "9788026008491" . . . . . "Plze\u0148" . "Plze\u0148" . "\u010Ceskoslovensk\u00E1 biologick\u00E1 spole\u010Dnost a L\u00E9ka\u0159sk\u00E1 fakulta UK v Plzni" . "5"^^ . . "The cell damage and regeneration in the immature brain and glioma cultures irradiated by epithermal neutron beam of the LVR-15 nuclear reactor in \u0158e\u017E" . "RIV/26722445:_____/11:#0000651!RIV12-MPO-26722445" . "2"^^ . . "The cell damage and regeneration in the immature brain and glioma cultures irradiated by epithermal neutron beam of the LVR-15 nuclear reactor in \u0158e\u017E"@en . "Interaction of epithermal neutrons with boron-10 (10B) leads to a damage of tumor tissue conferred (circumscribed) even soliatary cells. The nuclear reactors used for tumor therapy (Boron-Neutron-Capture-Therapy, BNCT) require individual tuning and monitoring by physical and biological methods. Here, were report effects of epithermal beam of the LVR-15 in \u0158e\u017E (7.8x 108n/cm2, 9 MW, 16.1 cGy/min) on the immature rat brain and C6 glioma culture, the model developed by us for this purpose (Mares et al. 1997, Burian et al. Kagawa). Irradiation of animals for 4 to 7 minutes induced the dose- and the cell differentiation degree- dependent apoptosis-like death in the cerebellum and forebrain, exceeding 2.1 times a gamma radiation equivalent. 3 days later, a dose inverse regeneration was evident in the cerebellum. In cultures irradiated for 30 to 45 min, the cells slowed-down cycling and cell death reaching a peak value at 72 to 96 h." . "2"^^ .