. . . . "Distal intramural spread of rectal cancer" . "V\u00E1vra, Petr" . . "37" . . "Distal intramural spread of rectal cancer" . "Distal intramural spread of rectal cancer"@en . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "7"^^ . "rectal cancer; surgery; distal intramural spread; surgical oncology; histopathology; tumor staging"@en . . . . . . "Pelik\u00E1n, Anton" . . "7"^^ . "5"^^ . "RIV/00843989:_____/05:00013318!RIV10-MZ0-00843989" . "V" . "Distal intramural spread of rectal cancer"@en . "[E9BA2F6F54DB]" . "Rydlov\u00E1, Marie" . . . . "BACKGROUND: The Czech Republic is one of the countries with the highest incidence of rectal cancer. Distal intramural spread below the palpable edge of a rectal cancer is unusual and a sign of very advanced or highly malignant disease. Submucosal spread occurs in approximately 10% of cases and indicates poor prognosis, regardless of type of operation. METHODS: In our study we focused on patients with rectal cancer who were operated at the Department of Surgery at the University Hospital of Ostrava within a period of three years (from 2000 to 2002).RESULTS: Our data show that submucosal tumor spread decreased at increasing distances from aboral tumor margin, an observation going in line with the literature. Submucosal tumor spread has been assessed in 11.8% of cases. CONCLUSIONS: Tumor spread was not found lower than 5 cm below the bottom margin of the tumor. Microscopic spread below the bottom margin of the tumor was observed in medium or low differentiated adenocarcinoma."@en . "European Surgery" . . "Mart\u00EDnek, Lubom\u00EDr" . "4" . . "V\u00E1vrov\u00E1, Michaela" . "Gu\u0148kov\u00E1, Petra" . "BACKGROUND: The Czech Republic is one of the countries with the highest incidence of rectal cancer. Distal intramural spread below the palpable edge of a rectal cancer is unusual and a sign of very advanced or highly malignant disease. Submucosal spread occurs in approximately 10% of cases and indicates poor prognosis, regardless of type of operation. METHODS: In our study we focused on patients with rectal cancer who were operated at the Department of Surgery at the University Hospital of Ostrava within a period of three years (from 2000 to 2002).RESULTS: Our data show that submucosal tumor spread decreased at increasing distances from aboral tumor margin, an observation going in line with the literature. Submucosal tumor spread has been assessed in 11.8% of cases. CONCLUSIONS: Tumor spread was not found lower than 5 cm below the bottom margin of the tumor. Microscopic spread below the bottom margin of the tumor was observed in medium or low differentiated adenocarcinoma." . "518304" . . . "RIV/00843989:_____/05:00013318" . . "1682-8631" . "Gu\u0148ka, Igor" . . . .