"RIV/00216305:26310/11:PU93985" . "2"^^ . . "V\u00E1vrov\u00E1, Milada" . . "187250" . . . "[EA71E634D55A]" . "Dvo\u0159\u00E1kov\u00E1, Petra" . . . . "The assessment of contamination of selected river streams in Czech Republic by human and veterinary drug residues with using liquid and gas chromatography" . . . "The assessment of contamination of selected river streams in Czech Republic by human and veterinary drug residues with using liquid and gas chromatography"@en . "Lacina, Petr" . "surface water, drug residues, liquid chromatography, gas chromatography"@en . . "26310" . . "This study monitors presence of selected drug residues in two river streams in Czech Republic. Drugs and their residues are discharged to the sewer systems together with the urine and faeces and enter the sewage treatment plant, where they are not completely removed. They can enter to the environment, where they can induce negative effects on organisms in water ecosystem. The study applies high performance liquid chromatography with mass spectrometric detection (HPLC-MS) and comprehensive two-dimensional gas chromatography with mass spectrometric detection Time-of-Flight (GCxGC-TOF MS) for determination of selected drug residues. HPLC-MS was used for determination of drugs from the group of sulfonamide antibiotics (sulfaacetamide, sulfadiazine, sulfathiazole, sulfapyridine, sulfamerazine, sulfamethazine, sulfamethoxazole), used mainly in veterinary medicine, and GCxGC-TOF MS was used for determination of drugs from the group of non-steroidal anti-inflammatory drugs (salicylic acid, clofibric acid, ibu" . "S" . "This study monitors presence of selected drug residues in two river streams in Czech Republic. Drugs and their residues are discharged to the sewer systems together with the urine and faeces and enter the sewage treatment plant, where they are not completely removed. They can enter to the environment, where they can induce negative effects on organisms in water ecosystem. The study applies high performance liquid chromatography with mass spectrometric detection (HPLC-MS) and comprehensive two-dimensional gas chromatography with mass spectrometric detection Time-of-Flight (GCxGC-TOF MS) for determination of selected drug residues. HPLC-MS was used for determination of drugs from the group of sulfonamide antibiotics (sulfaacetamide, sulfadiazine, sulfathiazole, sulfapyridine, sulfamerazine, sulfamethazine, sulfamethoxazole), used mainly in veterinary medicine, and GCxGC-TOF MS was used for determination of drugs from the group of non-steroidal anti-inflammatory drugs (salicylic acid, clofibric acid, ibu"@en . . . . "RIV/00216305:26310/11:PU93985!RIV12-MSM-26310___" . "The assessment of contamination of selected river streams in Czech Republic by human and veterinary drug residues with using liquid and gas chromatography" . "3"^^ . "The assessment of contamination of selected river streams in Czech Republic by human and veterinary drug residues with using liquid and gas chromatography"@en . . . .