. "3"^^ . . . "Stereoselective Synthesis of the Key Intermediates of the HIV Protease Inhibitor Fosamprenavir and Its Diastereomer" . . "Hanusek, Ji\u0159\u00ED" . . . . "Sedl\u00E1k, Milo\u0161" . . "Highly stereoselective Henry reaction has been used in the synthesis of the fosamprenavir precursor (2S,3R)-N-tert-butyl-oxycarbonyl-2-amino-3-hydroxy-1-phenyl-4-nitrobutane and its 2S, 3S diasteromer from N-tert-butyloxycarbonyl-(S)-phenylalaninal and nitromethane. The complex of (2S,5R)- or (2R,5S)-5-isopropyl-5-methyl-2-(pyridine-2-yl)imidazolidine-4-one with copper(II) acetate has been used as the catalyst which provided the product with 2S,3R absolute configuration (dr = 90: 10, overall yield 89%) or 2S,3S (dr = 99: 1, overall yield 94%), respectively."@en . "Stereoselective Synthesis of the Key Intermediates of the HIV Protease Inhibitor Fosamprenavir and Its Diastereomer"@en . "P(EE2.3.30.0021)" . "Drabina, Pavel" . . "DE - Spolkov\u00E1 republika N\u011Bmecko" . "ligands; homogenous catalysis; HIV; diastereoselectivity; aldol reaction"@en . "Highly stereoselective Henry reaction has been used in the synthesis of the fosamprenavir precursor (2S,3R)-N-tert-butyl-oxycarbonyl-2-amino-3-hydroxy-1-phenyl-4-nitrobutane and its 2S, 3S diasteromer from N-tert-butyloxycarbonyl-(S)-phenylalaninal and nitromethane. The complex of (2S,5R)- or (2R,5S)-5-isopropyl-5-methyl-2-(pyridine-2-yl)imidazolidine-4-one with copper(II) acetate has been used as the catalyst which provided the product with 2S,3R absolute configuration (dr = 90: 10, overall yield 89%) or 2S,3S (dr = 99: 1, overall yield 94%), respectively." . "107954" . "RIV/00216275:25310/13:39896100" . "Synlett" . . . . "25310" . . . "4"^^ . "Panov, Illia" . "10.1055/s-0033-1338803" . "RIV/00216275:25310/13:39896100!RIV14-MSM-25310___" . . . "0936-5214" . "10" . "[1D7304E5C4CD]" . . "4"^^ . . . "000320576300023" . "Stereoselective Synthesis of the Key Intermediates of the HIV Protease Inhibitor Fosamprenavir and Its Diastereomer" . . . "Stereoselective Synthesis of the Key Intermediates of the HIV Protease Inhibitor Fosamprenavir and Its Diastereomer"@en . "24" .