. . "Imramovsk\u00FD, Ale\u0161" . "P(GAP106/11/0058), Z(MSM0021627501)" . . "17" . "Current Pharmaceutical Design" . "Recent Advances in the Design and Synthesis of Prednisolone and Methylprednisolone Conjugates"@en . "Recent Advances in the Design and Synthesis of Prednisolone and Methylprednisolone Conjugates"@en . "3"^^ . . . "Glucocorticoid drugs are commonly used in the treatment of many acute and chronic inflammatory diseases. However, application of these steroids is limited because of their physico-chemical properties, such as very low water solubility. Glucocorticoids also exhibit serious adverse side effects. Therefore, new drug delivery systems are being developed, with the aim of improving the physicochemical properties of glucocorticoids while avoiding undesirable side effects associated with systemic administration. Here we discuss the design and synthesis of conjugates of prednisolone (PD), methylprednisolone (MPD) and similar glucocorticoids."@en . "3"^^ . "Recent Advances in the Design and Synthesis of Prednisolone and Methylprednisolone Conjugates" . . "Recent Advances in the Design and Synthesis of Prednisolone and Methylprednisolone Conjugates" . . "000299637000009" . "25310" . "19"^^ . "Glucocorticoid drugs are commonly used in the treatment of many acute and chronic inflammatory diseases. However, application of these steroids is limited because of their physico-chemical properties, such as very low water solubility. Glucocorticoids also exhibit serious adverse side effects. Therefore, new drug delivery systems are being developed, with the aim of improving the physicochemical properties of glucocorticoids while avoiding undesirable side effects associated with systemic administration. Here we discuss the design and synthesis of conjugates of prednisolone (PD), methylprednisolone (MPD) and similar glucocorticoids." . "AE - St\u00E1t Spojen\u00E9 arabsk\u00E9 emir\u00E1ty" . . . . "Prednisolone; Conjugates; methylprednisolone; Glucocorticoid drugs"@en . . "225893" . "1381-6128" . . . "32" . . "RIV/00216275:25310/11:39892211" . . . . "[F4E26F2C0F54]" . . . "B\u00EDlkov\u00E1, Eli\u0161ka" . "RIV/00216275:25310/11:39892211!RIV12-GA0-25310___" . . . "Sedl\u00E1k, Milo\u0161" .