. . "The determination of coproporphyrin I and III in human urine using an HPLC with fluorescence detection" . . . "16" . "The determination of selected porphyrins, especially of coproporphyrin I and III is presently the most reliable direct approach to the screening of porphyrias. An HPLC method for the simultaneous measurement of coproporphyrin I and III in urine samples has been developed and evaluated. Separation of coproporphyrin I and III from interfering substances was achieved on reversed phase HPLC with gradient elution and fluorescence detection. Analytical performance of this method is satisfactory for both coproporphyrin I and coproporphyrin III: the intra-assay and inter-assay coefficients of variation were below 10 %. Quantitative recoveries from spiked urine were between 85.0 and 101.1 %. The limit of detection was 3.0 and 2.3 ug/L, respectively. The preliminary reference ranges of coproporphyrin I and III in a group of donors are 5.0 51.6 ug/L (0.59 3.20 ug/mmol of creatinine) and 14.9 65.4 ug/L (0.98 8.21 ug/mmol of creatinine). The presented method is inexpensive and suitable for screening of porphyrias."@en . . . "CZ - \u010Cesk\u00E1 republika" . "prosinec" . "The determination of selected porphyrins, especially of coproporphyrin I and III is presently the most reliable direct approach to the screening of porphyrias. An HPLC method for the simultaneous measurement of coproporphyrin I and III in urine samples has been developed and evaluated. Separation of coproporphyrin I and III from interfering substances was achieved on reversed phase HPLC with gradient elution and fluorescence detection. Analytical performance of this method is satisfactory for both coproporphyrin I and coproporphyrin III: the intra-assay and inter-assay coefficients of variation were below 10 %. Quantitative recoveries from spiked urine were between 85.0 and 101.1 %. The limit of detection was 3.0 and 2.3 ug/L, respectively. The preliminary reference ranges of coproporphyrin I and III in a group of donors are 5.0 51.6 ug/L (0.59 3.20 ug/mmol of creatinine) and 14.9 65.4 ug/L (0.98 8.21 ug/mmol of creatinine). The presented method is inexpensive and suitable for screening of porphyrias." . . . . "The determination of coproporphyrin I and III in human urine using an HPLC with fluorescence detection" . "[C3541E4C22DC]" . . . "1211-5541" . "RIV/00216275:25310/10:39881874" . . "The determination of coproporphyrin I and III in human urine using an HPLC with fluorescence detection"@en . . "RIV/00216275:25310/10:39881874!RIV11-MSM-25310___" . . "253737" . . "4"^^ . "S" . . "Frohlichov\u00E1, Martina" . "Kan\u010F\u00E1r, Roman" . "5"^^ . "screening; porphyrias; high-performance liquid chromatography with fluorescence detection; coproporphyrin I and III"@en . . . "Scientific Papers of the University of Pardubice, Series A, Faculty of Chemical Technology" . "The determination of coproporphyrin I and III in human urine using an HPLC with fluorescence detection"@en . "\u0160tramov\u00E1, Xenie" . "25310" . "12"^^ . "\u017D\u00E1kov\u00E1, Pavla" . "Bencov\u00E1, So\u0148a" .