"UK" . "[C438B973D7D3]" . "Elsevier" . . "Porovn\u00E1n\u00ED hladin celkov\u00E9ho homocysteinu v plazm\u011B mezi pacienty s pozitivn\u00EDm a negativn\u00EDm koronarografick\u00FDm n\u00E1lezem"@cs . . "Several clinical studies have indicated that high plasma homocysteine concentration is an independent risk factor for origin and progress of atherosclerosis. The grade of atherosclerotic changes in coronary arteries may be investigated with coronarography. The aim of study was to compare levels of total plasma homocysteine in two groups of patients with different coronarography findings. There were 50 patients (33 men and 17 women) with positive findings in the first group. The mean value of age was 65.5 ? 13.9. Positive coronarography was characterized as 50% or more stenosis at least in one of the epicardial coronary arteries. There were 46 patients (24 men and 22 women) with negative findings in the second group. The mean value of age was 61.5 ? 13.9. Negative coronarography was characterized as no stenosis at least in one of the epicardial coronary arteries. We have determined concentration of total plasma homocysteine using ion-paired reversed-phase HPLC with coulometric electrochemical detection"@en . "Comparison of levels of total plasma homocysteine in patients with positive coronarography and patients with negative coronarography" . "homocysteine; atherosclerosis"@en . . "Clin. Chim. Acta suppl." . . "1"^^ . "Skalick\u00FD, Ji\u0159\u00ED" . . . "Several clinical studies have indicated that high plasma homocysteine concentration is an independent risk factor for origin and progress of atherosclerosis. The grade of atherosclerotic changes in coronary arteries may be investigated with coronarography. The aim of study was to compare levels of total plasma homocysteine in two groups of patients with different coronarography findings. There were 50 patients (33 men and 17 women) with positive findings in the first group. The mean value of age was 65.5 ? 13.9. Positive coronarography was characterized as 50% or more stenosis at least in one of the epicardial coronary arteries. There were 46 patients (24 men and 22 women) with negative findings in the second group. The mean value of age was 61.5 ? 13.9. Negative coronarography was characterized as no stenosis at least in one of the epicardial coronary arteries. We have determined concentration of total plasma homocysteine using ion-paired reversed-phase HPLC with coulometric electrochemical detection" . "Glasgow, Skotsko" . . "515882" . "2005-05-08+02:00"^^ . "Comparison of levels of total plasma homocysteine in patients with positive coronarography and patients with negative coronarography"@en . "N\u011Bkolik klinick\u00FDch studi\u00EDch nazna\u010Dilo, \u017Ee vysok\u00E1 hladina homocysteinu v plazm\u011B je nez\u00E1visl\u00FDm rizikov\u00FDm faktorem ateroskler\u00F3zy. Stupe\u0148 aterosklerotick\u00FDch zm\u011Bn v\u011Bn\u010Dit\u00FDch c\u00E9v mohou b\u00FDt zji\u0161t\u011Bny tzv. koronarografi\u00ED. C\u00EDlem t\u00E9to studie bylo porovnat hladiny celkov\u00E9ho homocysteinu u dvou skupin pacient\u016F s rozd\u00EDln\u00FDmi koronarografick\u00FDmi n\u00E1lezy. Prvn\u00ED skupinou bylo 50 pacient\u016F (33 mu\u017E\u016F a 17 \u017Een) s pozitivn\u00EDm n\u00E1lezem. Pr\u016Fm\u011Brn\u00FD v\u011Bk pacient\u016F byl 65,5 ? 13,9 let. Pozitivn\u00ED koronarografie byla charakterizov\u00E1na jako 50-ti a v\u00EDce procentn\u00ED sten\u00F3za alespo\u0148 v jedn\u00E9 z v\u011Bn\u010Dit\u00FDch c\u00E9v. V druh\u00E9 skupin\u011B pacient\u016F s negativn\u00ED koronarografi\u00ED bylo 46 pacient\u016F (24 mu\u017E\u016F a 22 \u017Een). Pr\u016Fm\u011Brn\u00FD v\u011Bk pacient\u016F byl 61,5 ? 13,9 let. Negativn\u00ED koronarografie byla charakterizov\u00E1na jako \u017E\u00E1dn\u00E1 sten\u00F3za ve v\u011Bn\u010Dit\u00FDch c\u00E9v\u00E1ch. Celkov\u00FD homocystein v plazm\u011B jsme stanovovali pomoc\u00ED ionp\u00E1rov\u00E9 RP-HPLC s coulometrickou elektrochemickou detekc\u00ED. Tato metoda je levn\u00E1 s rychlou p\u0159\u00EDpravou vzorku a s dostate\u010Dn\u00FDmi analytick\u00FDmi parametry. Tato HPLC metoda s elek"@cs . "\u017D\u00E1kov\u00E1, Pavla" . . "3"^^ . . "Comparison of levels of total plasma homocysteine in patients with positive coronarography and patients with negative coronarography" . "RIV/00216275:25310/05:00003178" . . "RIV/00216275:25310/05:00003178!RIV08-MSM-25310___" . "Vojt\u00ED\u0161ek, Petr" . "4"^^ . "Kan\u010F\u00E1r, Roman" . . . "Z(MSM0021627502)" . "25310" . "Comparison of levels of total plasma homocysteine in patients with positive coronarography and patients with negative coronarography"@en . "Porovn\u00E1n\u00ED hladin celkov\u00E9ho homocysteinu v plazm\u011B mezi pacienty s pozitivn\u00EDm a negativn\u00EDm koronarografick\u00FDm n\u00E1lezem"@cs . . . . . "0009-8981" . "107" . .