"Synt\u00E9za, struktur\u00E1ln\u00ED studie, in vitro antitumorov\u00E1 a trypanocidaln\u00ED aktivita tetrakis(3-methoxypropyl)stananu a 3-methoxypropylstanyl chlorid\u016F"@cs . . . "Synthesis, Structural Study, In vitro Antitumour and Trypanocidal Activity of Tetrakis(3-methoxypropyl)tin and (3-Methoxypropyl)tin Chlorides"@en . "Synt\u00E9za, struktur\u00E1ln\u00ED studie, in vitro antitumorov\u00E1 a trypanocidaln\u00ED aktivita tetrakis(3-methoxypropyl)stananu a 3-methoxypropylstanyl chlorid\u016F"@cs . "Synt\u00E9za, struktur\u00E1ln\u00ED studie, in vitro antitumorov\u00E1 a trypanocidaln\u00ED aktivita tetrakis(3-methoxypropyl)stananu a 3-methoxypropylstanyl chlorid\u016F"@cs . "4"^^ . "The set of four water-soluble (3-methoxypropyl)stannanes with the general formula (CH3OCH2CH2CH2)xSnCl4-x where x = 4 (1), x = 3 (2), x = 2 (3) and x = 1 (4), was prepared. For 3 and 4, which were isolated in crystalline state, it was shown by X ray diffraction that the tin atom is coordinated in distorted octahedral and trigonal-bipyramidal geometry, respectively, i.e. in both cases, the oxygen atoms of 3-methoxypropyl groups were coordinated to the central tin atom forming chelates. For all compounds, structures in CDCl3 and DMSO-d6 solutions were proposed from 13C and 119Sn NMR spectra. In CDCl3 solutions, the degree of donor-acceptor bonding between the central tin atom and oxygen atom of 3 methoxypropyl substituent was evaluated on the basis of 17O NMR chemical shifts and 3,6J(1H,119Sn) long-range coupling constants. Compounds 2 and 3 exhibited promising in vitro antitumour and trypanocidal activity." . "Tin; Chelates; O ligands; Structure elucidation; Drug research"@en . . "L\u00E9bl, Tom\u00E1\u0161" . "143-148" . . . "1" . "6"^^ . "The set of four water-soluble (3-methoxypropyl)stannanes with the general formula (CH3OCH2CH2CH2)xSnCl4-x where x = 4 (1), x = 3 (2), x = 2 (3) and x = 1 (4), was prepared. For 3 and 4, which were isolated in crystalline state, it was shown by X ray diffraction that the tin atom is coordinated in distorted octahedral and trigonal-bipyramidal geometry, respectively, i.e. in both cases, the oxygen atoms of 3-methoxypropyl groups were coordinated to the central tin atom forming chelates. For all compounds, structures in CDCl3 and DMSO-d6 solutions were proposed from 13C and 119Sn NMR spectra. In CDCl3 solutions, the degree of donor-acceptor bonding between the central tin atom and oxygen atom of 3 methoxypropyl substituent was evaluated on the basis of 17O NMR chemical shifts and 3,6J(1H,119Sn) long-range coupling constants. Compounds 2 and 3 exhibited promising in vitro antitumour and trypanocidal activity."@en . "Smi\u010Dka, Ale\u0161" . "1"^^ . "Brus, Ji\u0159\u00ED" . . "Synthesis, Structural Study, In vitro Antitumour and Trypanocidal Activity of Tetrakis(3-methoxypropyl)tin and (3-Methoxypropyl)tin Chlorides" . "RIV/00216275:25310/03:00000548" . "RIV/00216275:25310/03:00000548!RIV08-MSM-25310___" . . . "P(LN00A028)" . . . "[AC5488315623]" . "N" . . "Synthesis, Structural Study, In vitro Antitumour and Trypanocidal Activity of Tetrakis(3-methoxypropyl)tin and (3-Methoxypropyl)tin Chlorides" . . . "1434-1948" . "25310" . "European Journal of Inorganic Chemistry" . . "DE - Spolkov\u00E1 republika N\u011Bmecko" . . . "Synthesis, Structural Study, In vitro Antitumour and Trypanocidal Activity of Tetrakis(3-methoxypropyl)tin and (3-Methoxypropyl)tin Chlorides"@en . "Bruhn, Clemens" . . "630089" .