. . . . "The apical-basal axis of the early plant embryo determines the body plan of the adult organism. To establish a polarized embryonic axis, plants evolved a unique mechanism that involves directional, cell-to-cell transport of the growth regulator auxin. Auxin transport relies on PIN auxin transporters [1], whose polar subcellular localization determines the flow directionality. PIN-mediated auxin transport mediates the spatial and temporal activity of the auxin response machinery [2-7] that contributes to embryo patterning processes, including establishment of the apical (shoot) and basal (root) embryo poles [8]. However, little is known of upstream mechanisms guiding the (re)polarization of auxin fluxes during embryogenesis [9]. Here, we developed a model of plant embryogenesis that correctly generates emergent cell polarities and auxin-mediated sequential initiation of apical-basal axis of plant embryo."@en . "Friml, Ji\u0159\u00ED" . "24" . "Modeling Framework for the Establishment of the Apical-Basal Embryonic Axis in Plants"@en . "Robert Boisivon, Helene" . . . . . . . "Smith, Richard S" . . "Modeling Framework for the Establishment of the Apical-Basal Embryonic Axis in Plants" . "000328918900032" . . . . . . . "0960-9822" . . "RIV/00216224:14740/13:00072086!RIV14-MSM-14740___" . "14740" . . "P(ED1.1.00/02.0068), P(EE2.3.20.0043), P(EE2.3.30.0037)" . . "Robert Boisivon, Helene" . "Modeling Framework for the Establishment of the Apical-Basal Embryonic Axis in Plants"@en . . . "2"^^ . "Modeling Framework for the Establishment of the Apical-Basal Embryonic Axis in Plants" . "RIV/00216224:14740/13:00072086" . . "The apical-basal axis of the early plant embryo determines the body plan of the adult organism. To establish a polarized embryonic axis, plants evolved a unique mechanism that involves directional, cell-to-cell transport of the growth regulator auxin. Auxin transport relies on PIN auxin transporters [1], whose polar subcellular localization determines the flow directionality. PIN-mediated auxin transport mediates the spatial and temporal activity of the auxin response machinery [2-7] that contributes to embryo patterning processes, including establishment of the apical (shoot) and basal (root) embryo poles [8]. However, little is known of upstream mechanisms guiding the (re)polarization of auxin fluxes during embryogenesis [9]. Here, we developed a model of plant embryogenesis that correctly generates emergent cell polarities and auxin-mediated sequential initiation of apical-basal axis of plant embryo." . "10.1016/j.cub.2013.10.038" . "88840" . "4"^^ . "23" . "AUXIN TRANSPORT; COMPUTATIONAL MORPHODYNAMICS; ARABIDOPSIS EMBRYOGENESIS; PIN PROTEINS; POLARITY; EXPRESSION; EFFLUX; ABP1; ENDOCYTOSIS; ACTIVATION"@en . "Wabnik, Krzysztof" . . "Current Biology" . "[CEB02883358A]" . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "6"^^ . .