. . "Prediction of localization and interactions of apoptotic proteins"@en . "6"^^ . . "Prediction of localization and interactions of apoptotic proteins" . . . "Va\u0159echa, Miroslav" . . "Prediction of localization and interactions of apoptotic proteins" . "[6ED968DF0BB5]" . . . "335450" . . . "AIF; apoptosis-inducing factor; AMID; AIF-homologous mitochondrion-associated inducer of death; endonuclease G; heat shock protein; DNA topoisomerase II; CPS-6; CED-3 protease suppressor; WAH-1"@en . "RIV/00216224:14330/09:00029126!RIV11-GA0-14330___" . "14330" . "Journal of Biomedical Science" . . "000268893400002" . "P(2B06052), P(GP204/05/P090), P(LC535), Z(MSM0021622419)" . "Ulman, Vladim\u00EDr" . "59" . . "RIV/00216224:14330/09:00029126" . . "We found the AMID protein to be cytoplasmic, most probably incorporated into the cytoplasmic side of the membranes of various organelles. The highest concentration of AMID was observed associated with the Golgi. We did not observe its translocation into the nucleus during apoptosis. The proposed role of AMID in apoptosis was thus not observed. Bioinformatic predictions were conducted to analyze the interactions of the studied proteins with each other and with other possible partners. We conducted molecular modelling of proteins with unknown 3D structure: endonuclease G, CPS-6, WAH-1, and HSP70-1. These models were then refined by MolProbity server and employed in molecular docking simulations of interactions. Our results present new data about the structure, localization, functions and interactions of proteins AMID, AIF, endonuclease G, and other proteins."@en . . "Kozubek, Michal" . "14"^^ . . . . "Prediction of localization and interactions of apoptotic proteins"@en . . . . . "Amrichov\u00E1, Jana" . . . "Zimmermann, Michal" . . . . "Matula, Pavel" . "We found the AMID protein to be cytoplasmic, most probably incorporated into the cytoplasmic side of the membranes of various organelles. The highest concentration of AMID was observed associated with the Golgi. We did not observe its translocation into the nucleus during apoptosis. The proposed role of AMID in apoptosis was thus not observed. Bioinformatic predictions were conducted to analyze the interactions of the studied proteins with each other and with other possible partners. We conducted molecular modelling of proteins with unknown 3D structure: endonuclease G, CPS-6, WAH-1, and HSP70-1. These models were then refined by MolProbity server and employed in molecular docking simulations of interactions. Our results present new data about the structure, localization, functions and interactions of proteins AMID, AIF, endonuclease G, and other proteins." . "5"^^ . . . "16" . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . . "1021-7770" . .