. "671950" . "14"^^ . . "The 3D structure of human chromosomes in cell nuclei"@en . "Kozubek, Stanislav" . . . . . . "10" . "Luk\u00E1\u0161ov\u00E1, Emilie" . "Chromosome Research" . "The spatial arrangement of some genetic elements relative to chromosome territories and in parallel with the cell nucleus was investigated in human lymphocytes. The structure of the chromosome territories was studied in chromosomes containing regions (clusters) of highly expressed genes (HSA 9, 17) and those without such clusters (HSA 8, 13). In chromosomes containing highly expressed regions, the elements pertaining to these regions were found close to the centre of the nucleus on the inner sides of chromosome territories; those pertaining to regions with low expression were localized close to the nuclear membrane on the opposite sides of the territories. In chromosomes with generally low expression (HSA 8, 13), the elements investigated were found symmetrically distributed over the territories." . "RIV/00216224:14330/02:00006557" . "The spatial arrangement of some genetic elements relative to chromosome territories and in parallel with the cell nucleus was investigated in human lymphocytes. The structure of the chromosome territories was studied in chromosomes containing regions (clusters) of highly expressed genes (HSA 9, 17) and those without such clusters (HSA 8, 13). In chromosomes containing highly expressed regions, the elements pertaining to these regions were found close to the centre of the nucleus on the inner sides of chromosome territories; those pertaining to regions with low expression were localized close to the nuclear membrane on the opposite sides of the territories. In chromosomes with generally low expression (HSA 8, 13), the elements investigated were found symmetrically distributed over the territories."@en . "Falk, Martin" . . "Amrichov\u00E1, Jana" . . "7" . "NL - Nizozemsko" . "The 3D structure of human chromosomes in cell nuclei"@en . . "Kozubek, Michal" . . . "chromosome structure; confocal microscopy; mathematical models; nuclear architecture"@en . "The 3D structure of human chromosomes in cell nuclei" . . "The 3D structure of human chromosomes in cell nuclei" . "5"^^ . . . "5"^^ . . . . . "P(GA202/01/0197), P(GA301/01/0186), P(IAA1065203), P(IBS5004010), P(NC5955), Z(AV0Z5004920), Z(MSM 143300002)" . . "0967-3849" . . . . . . . . "RIV/00216224:14330/02:00006557!RIV11-AV0-14330___" . "[B2312DE92203]" . "14330" .