"Docosahexaenoic fatty acid (DHA) in the regulation of colon cell growth and cell death: A review" . "polyunsaturated fatty acids; docosahexaenoic acid; colon cancer; apoptosis; cell signalling; anticancer therapy"@en . . "Docosahexaenoic fatty acid (DHA) in the regulation of colon cell growth and cell death: A review"@en . "Skender, Belma" . . . "156" . "1213-8118" . "[B858FCBEA50B]" . "BIOMEDICAL PAPERS-OLOMOUC" . "CZ - \u010Cesk\u00E1 republika" . "I, P(GAP301/11/1730), P(GD303/09/H048), S, Z(AV0Z50040702), Z(MSM0021622430)" . "131826" . . "Docosahexaenoic fatty acid (DHA) in the regulation of colon cell growth and cell death: A review"@en . . "3" . . . . "000310725900001" . "14"^^ . "RIV/00216224:14310/12:00067589!RIV14-MSM-14310___" . . . . "Vaculov\u00E1 Hyr\u0161lov\u00E1, Alena" . . . . "Background. Experimental, epidemiological and clinical data substantiate the beneficial role of n-3 polyunsaturated fatty acids (PUFAs) in preventing inflammation and cancer of the colon. This review covers the unsaturated docosahexaenoic fatty acid (DHA), describes some of its important cellular and molecular mechanisms, its interaction with another dietary lipid, butyrate and with endogenous apoptotic regulators of the tumour necrosis factor (TNF) family. We also discuss the clinical impact of this knowledge and the use of these lipids in colon cancer prevention and treatment. Results. From the literature, DHA has been shown to suppress the growth, induce apoptosis in colon cancer cells in vitro and decrease the incidence and growth of experimental tumours in vivo. Based on these data and our own experimental results, we describe and discuss the possible mechanisms of DHA anticancer effects at various levels of cell organization."@en . "Background. Experimental, epidemiological and clinical data substantiate the beneficial role of n-3 polyunsaturated fatty acids (PUFAs) in preventing inflammation and cancer of the colon. This review covers the unsaturated docosahexaenoic fatty acid (DHA), describes some of its important cellular and molecular mechanisms, its interaction with another dietary lipid, butyrate and with endogenous apoptotic regulators of the tumour necrosis factor (TNF) family. We also discuss the clinical impact of this knowledge and the use of these lipids in colon cancer prevention and treatment. Results. From the literature, DHA has been shown to suppress the growth, induce apoptosis in colon cancer cells in vitro and decrease the incidence and growth of experimental tumours in vivo. Based on these data and our own experimental results, we describe and discuss the possible mechanisms of DHA anticancer effects at various levels of cell organization." . "Docosahexaenoic fatty acid (DHA) in the regulation of colon cell growth and cell death: A review" . "14310" . . "RIV/00216224:14310/12:00067589" . . "1"^^ . . . "3"^^ . "10.5507/bp.2012.093" . . . . "Hofmanov\u00E1, Ji\u0159ina" . . . . .