. "Heterocycles; Indoles; Natural products; Phytoalexins; Glyoxylindoles"@en . "12"^^ . "GLYOXYL ANALOGS OF INDOLE PHYTOALEXINS: SYNTHESIS AND ANTICANCER ACTIVITY" . . "S" . . . "Kutschy, Peter" . . . . "0010-0765" . . "Glyoxyl analogs of indole phytoalexins brassinin, 1-methoxybrassinin, brassitin, 1-methoxybrassitin and 1-methoxybrassenin B were prepared, using (1H-indol-3-yl)-, (1-methoxyindol- 3-yl)- and [1-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)indol-3-yl]glyoxyl chlorides as starting compounds. Synthesized products were examined for their antiproliferative activity against human cancer cell lines Jurkat (T-cell acute lymphoblastic leukemia), MCF-7 (breast adenocarcinoma, estrogen receptor-positive), MDA-MB-231 (breast adenocarcinoma, estrogen receptor-negative), HeLa (cervical adenocarcinoma), CCRF-CEM cell line (T-cell acute lymphoblastic leukemia) and A-549 cell line (lung adenocarcinoma), and their activity compared with natural phytoalexins and corresponding (1H-indol-3-yl)acetic acid derivatives. The highest potency with IC50 3.3-66.1 m\u00EDmol l-1 was found for glyoxyl analogs of 1-methoxybrassenin B." . "Hromj\u00E1kov\u00E1, Tatiana" . . "[384DB899CC29]" . "RIV/00216224:14310/10:00044943" . . "GLYOXYL ANALOGS OF INDOLE PHYTOALEXINS: SYNTHESIS AND ANTICANCER ACTIVITY"@en . "8" . "\u010Curillov\u00E1, Zuzana" . "Pil\u00E1tov\u00E1, Martina" . "RIV/00216224:14310/10:00044943!RIV11-MSM-14310___" . "260857" . "GLYOXYL ANALOGS OF INDOLE PHYTOALEXINS: SYNTHESIS AND ANTICANCER ACTIVITY"@en . "CZ - \u010Cesk\u00E1 republika" . "S\u00FDkora, Andrej" . "9"^^ . "Collection of Czechoslovak Chemical Communications" . "2010048" . . "75" . . . "Pazdera, Pavel" . . "1"^^ . "Glyoxyl analogs of indole phytoalexins brassinin, 1-methoxybrassinin, brassitin, 1-methoxybrassitin and 1-methoxybrassenin B were prepared, using (1H-indol-3-yl)-, (1-methoxyindol- 3-yl)- and [1-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)indol-3-yl]glyoxyl chlorides as starting compounds. Synthesized products were examined for their antiproliferative activity against human cancer cell lines Jurkat (T-cell acute lymphoblastic leukemia), MCF-7 (breast adenocarcinoma, estrogen receptor-positive), MDA-MB-231 (breast adenocarcinoma, estrogen receptor-negative), HeLa (cervical adenocarcinoma), CCRF-CEM cell line (T-cell acute lymphoblastic leukemia) and A-549 cell line (lung adenocarcinoma), and their activity compared with natural phytoalexins and corresponding (1H-indol-3-yl)acetic acid derivatives. The highest potency with IC50 3.3-66.1 m\u00EDmol l-1 was found for glyoxyl analogs of 1-methoxybrassenin B."@en . "Moj\u017Ei\u0161, J\u00E1n" . "GLYOXYL ANALOGS OF INDOLE PHYTOALEXINS: SYNTHESIS AND ANTICANCER ACTIVITY" . . "Mezencev, Roman" . "Repovsk\u00E1, M\u00E1ria" . "14310" . .