. . "\u0160marda, Jan" . . "Growth Differentiation Factor-15 secreted by prostate cancer cells inhibits differentiation of osteoclasts"@en . "Growth Differentiation Factor-15 secreted by prostate cancer cells inhibits differentiation of osteoclasts" . "Growth Differentiation Factor-15 secreted by prostate cancer cells inhibits differentiation of osteoclasts" . "P(GA301/09/1115), S, Z(MSM0021622415)" . . "RIV/00216224:14310/09:00036202!RIV11-GA0-14310___" . "316732" . . . "14310" . . "Sou\u010Dek, Karel" . . . . . "the FEBS Journal, 256, Suppl. 1" . . . "Prostate cancer is a common disease in industrial countries. Prostate tumors preferentially disseminate to bones and induce significant rearrangement of the bone architecture. T The aim of this study is to characterize effects of growth differentiation factor-15 (GDF-15) secreted by prostate cancer cells on the osteoclastic differentiation pathway. This study documents that GDF-15 both as purified substance and as unpurified product secreted by prostate cancer cells strongly interferes with differentiation of osteoclasts by inhibiting expression and activity of NFkB and c-Fos."@en . "2009-01-01+01:00"^^ . . "1742-464X" . "[3D269B365A7B]" . . . "Prostate cancer is a common disease in industrial countries. Prostate tumors preferentially disseminate to bones and induce significant rearrangement of the bone architecture. T The aim of this study is to characterize effects of growth differentiation factor-15 (GDF-15) secreted by prostate cancer cells on the osteoclastic differentiation pathway. This study documents that GDF-15 both as purified substance and as unpurified product secreted by prostate cancer cells strongly interferes with differentiation of osteoclasts by inhibiting expression and activity of NFkB and c-Fos." . . "Slab\u00E1kov\u00E1, Eva" . . "2"^^ . . "FEBS" . . "Prague, Czech Republic" . "Growth Differentiation Factor-15 secreted by prostate cancer cells inhibits differentiation of osteoclasts"@en . . "Prague, Czech Republic" . . "4"^^ . "RIV/00216224:14310/09:00036202" . "4"^^ . "Va\u0148hara, Petr" . "GDF-15; osteoclats; prostate cancer"@en .