. . "P(GA204/08/1530), P(LC06004), Z(AV0Z50040507), Z(MSM0021622415)" . "DNA hypomethylation does not regulate the length of telomeres in plants"@en . . . . . . "Hypomethylace DNA neovliv\u0148uje d\u00E9lku rostlinn\u00FDch telomer"@cs . . "Fajkus, Ji\u0159\u00ED" . "\u0106esk\u00E1 spole\u010Dnost experiment\u00E1ln\u00ED biologie rostlin" . "telomeres; epigenetics; methylation; DHPA; HRS60; tobacco; DNA hypomethylation"@en . "2009-10-11+02:00"^^ . . "Praha" . . "Telomery, nukleoproteinov\u00E9 struktury, jsou velmi d\u016Fle\u017Eit\u00E9 pro udr\u017Een\u00ED celistvosti eukaryotick\u00FDch chromozom\u016F a zm\u011Bna jejich d\u00E9lky rozhoduje bu\u010F o dal\u0161\u00EDm bun\u011B\u010Dn\u00E9m d\u011Blen\u00ED, nebo o navozen\u00ED bun\u011B\u010Dn\u00E9 smrti. Dosud nebylo mnoho zn\u00E1mo ohledn\u011B epigenetick\u00E9 regulace d\u00E9lky telomer, nicm\u00E9n\u011B posledn\u00ED v\u00FDsledky ukazuj\u00ED na regulaci d\u00E9lky telomer sav\u010D\u00EDch bun\u011Bk pomoc\u00ED zm\u011Bny methyla\u010Dn\u00EDho stavu bu\u0148ky. Tato pr\u00E1ce se zab\u00FDv\u00E1 vlivem chemicky navozen\u00E9 hypomethylace DNA a histon\u016F na d\u00E9lku telomer u Nicotiana tabacum. Prozatimn\u00ED v\u00FDsledky prok\u00E1zaly markantn\u00ED sn\u00ED\u017Een\u00ED methylace DNA v subtelomerov\u00FDch oblastech, kter\u00E9 ov\u0161em nevedlo ke zm\u011Bn\u011B d\u00E9lky telomer, ani ke zm\u011Bn\u011B nukleozom\u00E1ln\u00EDho vinut\u00ED na telomer\u00E1ch."@cs . . "Hypomethylace DNA neovliv\u0148uje d\u00E9lku rostlinn\u00FDch telomer"@cs . . "1"^^ . . "[4111411CE643]" . "Mozgov\u00E1, Iva" . "RIV/00216224:14310/09:00028753" . "1213-6670" . "318239" . "Telomery, nukleoproteinov\u00E9 struktury, jsou velmi d\u016Fle\u017Eit\u00E9 pro udr\u017Een\u00ED celistvosti eukaryotick\u00FDch chromozom\u016F a zm\u011Bna jejich d\u00E9lky rozhoduje bu\u010F o dal\u0161\u00EDm bun\u011B\u010Dn\u00E9m d\u011Blen\u00ED, nebo o navozen\u00ED bun\u011B\u010Dn\u00E9 smrti. Dosud nebylo mnoho zn\u00E1mo ohledn\u011B epigenetick\u00E9 regulace d\u00E9lky telomer, nicm\u00E9n\u011B posledn\u00ED v\u00FDsledky ukazuj\u00ED na regulaci d\u00E9lky telomer sav\u010D\u00EDch bun\u011Bk pomoc\u00ED zm\u011Bny methyla\u010Dn\u00EDho stavu bu\u0148ky. Tato pr\u00E1ce se zab\u00FDv\u00E1 vlivem chemicky navozen\u00E9 hypomethylace DNA a histon\u016F na d\u00E9lku telomer u Nicotiana tabacum. Prozatimn\u00ED v\u00FDsledky prok\u00E1zaly markantn\u00ED sn\u00ED\u017Een\u00ED methylace DNA v subtelomerov\u00FDch oblastech, kter\u00E9 ov\u0161em nevedlo ke zm\u011Bn\u011B d\u00E9lky telomer, ani ke zm\u011Bn\u011B nukleozom\u00E1ln\u00EDho vinut\u00ED na telomer\u00E1ch." . . . . . . "Majerov\u00E1, Eva" . "RIV/00216224:14310/09:00028753!RIV10-MSM-14310___" . . "3"^^ . . . "Hotel Bezru\u010D, Beskydy" . "3"^^ . "Hypomethylace DNA neovliv\u0148uje d\u00E9lku rostlinn\u00FDch telomer" . . "Hypomethylace DNA neovliv\u0148uje d\u00E9lku rostlinn\u00FDch telomer" . . . . . "DNA hypomethylation does not regulate the length of telomeres in plants"@en . "14310" . "Telomeres, the nucleoprotein structures, are very important to eukaryotic chromosome stabilization and changes in their length are critical for either undergoing next cell cycle or for induction of apoptosis. So far there were not much known about the epigenetic regulation of telomere length, nevertheless some results show that mammalian telomeres can be affected by changes in DNA and histone methylation pattern. This work is concerned of the effect of chemically induced hypomethylation of DNA and histones on telomere length in Nicotiana tabacum. Temporary results approve striking decrease in DNA methylation in subtelomeric regions, which did not lead to any change in telomeric length neither in telomere nucleozomal winding."@en . "Bulletin \u010Cesk\u00E9 spole\u010Dnosti experiment\u00E1ln\u00ED biologie rostlin a Fyziologick\u00E9 sekce Slovensk\u00E9 botanick\u00E9 spole\u010Dnosti" .