"14310" . "Kub\u00ED\u010Dek, Karel" . . "Carlomagno, Teresa" . "7"^^ . "11" . "RIV/00216224:14310/07:00032343" . "RIV/00216224:14310/07:00032343!RIV10-MSM-14310___" . "Reese, Marcel" . "Fits in a pocket: The binding mode of epothilone A (EpoA) to tubulin is determined by NMR spectroscopy in aqueous solution. The results explain the existing structure-activity relationship data for epothilones with both native and mutant tubulins, and support the existence of a common pharmacophore for EpoA and paclitaxel." . . "Fits in a pocket: The binding mode of epothilone A (EpoA) to tubulin is determined by NMR spectroscopy in aqueous solution. The results explain the existing structure-activity relationship data for epothilones with both native and mutant tubulins, and support the existence of a common pharmacophore for EpoA and paclitaxel."@en . . . . "[8F663B3C7587]" . . . . "1"^^ . "46" . "Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution" . "Sanchez-Pedregal, Victor M" . "Griesinger, Christian" . "DE - Spolkov\u00E1 republika N\u011Bmecko" . "Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution"@en . . "Angewandte Chemie International Edition" . "452847" . . "Meiler, Jens" . . "Blommers, Marcel J" . . "epothilones; NMR spectroscopy; structure elucidation; structure-activity relationships; tubulins"@en . "Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution" . . "V" . "5"^^ . . . "1433-7851" . "Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution"@en . .