"P(LC06034), S, V, Z(MSM0021622415)" . "RIV/00216224:14310/07:00022291" . . . . . "Zdr\u00E1hal, Zbyn\u011Bk" . . . . "Kone\u010Dn\u00E1, Hana" . "GRAFT VERSUS HOST DISEASE AFTER ALLOGENEIC STEM CELL TRANSPLANTATION AND ITS PREDICTION BY PROTEOMIC APPROACHES"@en . "[79735B6D3832]" . . . "6"^^ . . . . "acute graft-versus-host disease; proteomics; biomarkers"@en . . "Background: Acute graft versus host disease (GvHD) is a frequent complication of allogeneic stem cells transplantation (alloSCT). The rapid diagnosis of acute GvHD following alloSCT is important for optimizing the management of this life-threatening complication. Differentially expressed or excreted polypeptides and proteins have potential for early and accurate diagnosis of GvHD and other complications of allo-SCT. Aims: Search for blood plasma proteins useful as potential biomarkers for early detection of GvHD. Methods: 2-dimensional gel electrophoresis (2-DE) was used for separation of blood plasma proteins. Proteins considered as potential biomarkers for early prediction of GvHD were selected by image analysis. Protein spots with different expression levels were characterized by matrix-assisted laser desorption/ionization - time of flight mass spectrometry (MALDI-TOF-MS) using peptide mass fingerprinting."@en . . "GRAFT VERSUS HOST DISEASE AFTER ALLOGENEIC STEM CELL TRANSPLANTATION AND ITS PREDICTION BY PROTEOMIC APPROACHES" . . . . "6"^^ . . "14310" . . "Background: Acute graft versus host disease (GvHD) is a frequent complication of allogeneic stem cells transplantation (alloSCT). The rapid diagnosis of acute GvHD following alloSCT is important for optimizing the management of this life-threatening complication. Differentially expressed or excreted polypeptides and proteins have potential for early and accurate diagnosis of GvHD and other complications of allo-SCT. Aims: Search for blood plasma proteins useful as potential biomarkers for early detection of GvHD. Methods: 2-dimensional gel electrophoresis (2-DE) was used for separation of blood plasma proteins. Proteins considered as potential biomarkers for early prediction of GvHD were selected by image analysis. Protein spots with different expression levels were characterized by matrix-assisted laser desorption/ionization - time of flight mass spectrometry (MALDI-TOF-MS) using peptide mass fingerprinting." . "Tomancov\u00E1, Alexandra" . "GRAFT VERSUS HOST DISEASE AFTER ALLOGENEIC STEM CELL TRANSPLANTATION AND ITS PREDICTION BY PROTEOMIC APPROACHES"@en . "\u0160edo, Ondrej" . "GRAFT VERSUS HOST DISEASE AFTER ALLOGENEIC STEM CELL TRANSPLANTATION AND ITS PREDICTION BY PROTEOMIC APPROACHES" . "423584" . . "Mayer, Ji\u0159\u00ED" . . "Posp\u00ED\u0161ilov\u00E1, \u0160\u00E1rka" . . . . "RIV/00216224:14310/07:00022291!RIV11-MSM-14310___" .