. "A case-control study of the relationship between 13 candidate genes and ADHD" . . "A case-control study of the relationship between 13 candidate genes and ADHD"@en . "Mike\u0161, Vladim\u00EDr" . . "P(NR8137), Z(MSM0021622413)" . . "7" . "\u0160taif, Radim" . "ADHD; polymorphism; DAT1; DRD2; COMT; MAOB; ACE; ANG; CCR5; BDNF; MU; IL-2; IL-6; TNF; M235T"@en . . "A case-control study of the relationship between 13 candidate genes and ADHD" . . . . "Pitelov\u00E1, Ren\u00E1ta" . "14310" . . "141B" . . "RIV/00216224:14310/06:00017436" . . . . "7"^^ . "Theiner, Pavel" . . . "American Journal of Medical Genetics" . . "CZ - \u010Cesk\u00E1 republika" . . "1552-4841" . "463425" . . . . "2"^^ . "7"^^ . . "A case-control study of the relationship between 13 candidate genes and ADHD"@en . . . "Attention deficit hyperactivity disorder (ADHD) is a multifactorial disorder with significant genetic contribution. Dopamine genes have been the initial candidates based on the site of the action of the psychostimulant drugs. The other genes from neurotransmitter and immune system are in focus too. We have investigated whether there is an association between ADHD and polymorphisms of 13 candidate genes: DAT1, DRD2, COMT, MAOB, ACE, ANG, CCR5, BDNF, MU, IL-2, IL-6, TNF-alpha, and M235T. The aim of our case-control study was to determine whether the ADHD boys (118) have different genotype and alelic frequencies of examined polymorphisms of the above mentioned genes compared to controls (153). No significant differences were found between groups of boys in allelic and genotype frequencies of COMT, MAOB, ACE, ANG, CCR5, BDNF, MU, IL-2, IL-6, TNF-alpha and M235T genes (p < 0.05)." . . . . "Drt\u00EDlkov\u00E1, Ivana" . . "[3ED23D33EE6E]" . . . . "\u0160er\u00FD, Omar" . "Lochman, Jan" . "RIV/00216224:14310/06:00017436!RIV10-MZ0-14310___" . "Attention deficit hyperactivity disorder (ADHD) is a multifactorial disorder with significant genetic contribution. Dopamine genes have been the initial candidates based on the site of the action of the psychostimulant drugs. The other genes from neurotransmitter and immune system are in focus too. We have investigated whether there is an association between ADHD and polymorphisms of 13 candidate genes: DAT1, DRD2, COMT, MAOB, ACE, ANG, CCR5, BDNF, MU, IL-2, IL-6, TNF-alpha, and M235T. The aim of our case-control study was to determine whether the ADHD boys (118) have different genotype and alelic frequencies of examined polymorphisms of the above mentioned genes compared to controls (153). No significant differences were found between groups of boys in allelic and genotype frequencies of COMT, MAOB, ACE, ANG, CCR5, BDNF, MU, IL-2, IL-6, TNF-alpha and M235T genes (p < 0.05)."@en . . . . . .