"14310" . . "RIV/00216224:14310/05:00014124" . "Cv-IIL: new lectin from human oportunistic pathogen Chromobacterium violaceum"@en . . "Cioci, Gianluca" . . "lectin; Chromobacterium violaceum; pathogen"@en . . "Imberty, Anne" . "CZ - \u010Cesk\u00E1 republika" . . "Pathogen adhesion to the host cell surface followed by its colonisation, invasion and infectivity is usually mediated by protein-carbohydrate interactions. Pseudomonas aeruginosa, an opportunistic pathogen responsible for numerous nosocomial infections in immunocopromised patients, produces a variety of carbohydrate-binding proteins that could be involved in host recognition and adhesion. One of them, PA-IIL, is a fucose binding lectin that is closely related to the virulence of the bacterium [1]. Searching in databases for proteins displaying sequence similarities to PA-IIL revealed new homologous proteins in other opportunistic pathogens like Chromobacterium violaceum. Human infection by Ch. violaceum is rare but when it occurs, it is associated with very high mortality rate [2]. The gene cv1741 coding a hypothetical protein similar to PA-IIL, was cloned and the resulting recombinant protein, CV-IIL, has been expressed in E. coli and purified to homogeneity." . "4/5/6" . "Perret, Stephanie" . . . "516704" . . . "RIV/00216224:14310/05:00014124!RIV10-MSM-14310___" . "Cv-IIL: new lectin from human oportunistic pathogen Chromobacterium violaceum" . "[8B75AC3B2103]" . . "2"^^ . "2"^^ . . "Glycoconjugate Journal" . "Cv-IIL: new lectin from human oportunistic pathogen Chromobacterium violaceum" . "0282-0080" . "Z(MSM0021622413)" . . "22" . . . "Wimmerov\u00E1, Michaela" . "Pokorn\u00E1, Martina" . . "Cv-IIL: new lectin from human oportunistic pathogen Chromobacterium violaceum"@en . . "Mitchell, Edward P." . "Pathogen adhesion to the host cell surface followed by its colonisation, invasion and infectivity is usually mediated by protein-carbohydrate interactions. Pseudomonas aeruginosa, an opportunistic pathogen responsible for numerous nosocomial infections in immunocopromised patients, produces a variety of carbohydrate-binding proteins that could be involved in host recognition and adhesion. One of them, PA-IIL, is a fucose binding lectin that is closely related to the virulence of the bacterium [1]. Searching in databases for proteins displaying sequence similarities to PA-IIL revealed new homologous proteins in other opportunistic pathogens like Chromobacterium violaceum. Human infection by Ch. violaceum is rare but when it occurs, it is associated with very high mortality rate [2]. The gene cv1741 coding a hypothetical protein similar to PA-IIL, was cloned and the resulting recombinant protein, CV-IIL, has been expressed in E. coli and purified to homogeneity."@en . "6"^^ .