"Molekulov\u011B Dynamick\u00E1 simulace flexibiln\u00EDch RNA motiv\u016F" . "42" . "P(LN00A016)" . . "Molecular Dynamics simulation of flexible RNA motifs"@en . "Molekulov\u011B Dynamick\u00E1 simulace flexibiln\u00EDch RNA motiv\u016F"@cs . "2004-05-05+02:00"^^ . "R\u00E1zga, Filip" . "Leontis, Neocles B." . "Ko\u010Da, Jaroslav" . . . . "RNA dynamics; flexibility"@en . "\u0160poner, Ji\u0159\u00ED" . "574425" . . "Molecular Dynamics simulation of flexible RNA motifs"@en . . . . . "Leontis, Neocles B." . "Molekulov\u00E1 dynamika je modern\u00ED v\u00FDpo\u010Detn\u00ED metoda, kter\u00E1 umo\u017E\u0148uje studovat funk\u010Dn\u011B v\u00FDznamn\u00E9 pohyby v biomakromolekul\u00E1ch. Tuto metodu je mo\u017En\u00E9 pou\u017E\u00EDt rovn\u011B\u017E pro vyhodnocen\u00ED efektu mutac\u00ED v RNA motivech. Molekulov\u011B dynamick\u00E9 simulace flexibiln\u00EDch a rigidn\u00EDch RNA motiv\u016F byly srovn\u00E1ny detailn\u00ED strukturn\u00ED a statistickou anal\u00FDzou. Modul\u00E1rn\u00ED charakter vybran\u00FDch RNA motiv\u016F byl studov\u00E1n na \u0161k\u00E1le des\u00EDtek nanosekund se zam\u011B\u0159en\u00EDm na RNA-RNA interakce zprost\u0159edkovan\u00E9 molekulami vody." . "Sborn\u00EDk abstrakt\u016F Studentsk\u00E1 v\u011Bdeck\u00E1 konference v oboru chemie a biochemie" . "Brno" . "Brno" . "Molekulov\u00E1 dynamika je modern\u00ED v\u00FDpo\u010Detn\u00ED metoda, kter\u00E1 umo\u017E\u0148uje studovat funk\u010Dn\u011B v\u00FDznamn\u00E9 pohyby v biomakromolekul\u00E1ch. Tuto metodu je mo\u017En\u00E9 pou\u017E\u00EDt rovn\u011B\u017E pro vyhodnocen\u00ED efektu mutac\u00ED v RNA motivech. Molekulov\u011B dynamick\u00E9 simulace flexibiln\u00EDch a rigidn\u00EDch RNA motiv\u016F byly srovn\u00E1ny detailn\u00ED strukturn\u00ED a statistickou anal\u00FDzou. Modul\u00E1rn\u00ED charakter vybran\u00FDch RNA motiv\u016F byl studov\u00E1n na \u0161k\u00E1le des\u00EDtek nanosekund se zam\u011B\u0159en\u00EDm na RNA-RNA interakce zprost\u0159edkovan\u00E9 molekulami vody."@cs . . "RIV/00216224:14310/04:00010020!RIV08-MSM-14310___" . "Molekulov\u011B Dynamick\u00E1 simulace flexibiln\u00EDch RNA motiv\u016F" . "[0ABE54273D34]" . "Explicit-solvent molecular dynamics simulation is powerful technique for exploring the functionally relevant motions of biological macromolecules and for evaluating the effects of mutations on motif dynamics. Simulations of flexible and rigid RNA motifs will be compared by detailed statistical and structural analysis.Mechanisms for modulating functionally significant flexibility will be discussed, emphasising the role of RNA-RNA interactions mediated by solvent molecules."@en . . "4"^^ . . "Masarykova univerzita v Brn\u011B. P\u0159\u00EDrodov\u011Bdeck\u00E1 fakulta. Sekce chemie" . . . "4"^^ . "Molekulov\u011B Dynamick\u00E1 simulace flexibiln\u00EDch RNA motiv\u016F"@cs . "RIV/00216224:14310/04:00010020" . "1"^^ . . . . "14310" .