"1"^^ . . "glycosyltransferase; mycobacterium tuberculosis; threading"@en . "3"^^ . . . "Glycosyltransferase prediction in Mycobacterium tuberculosis genome by threading" . . "RIV/00216224:14310/02:00007106!RIV08-MSM-14310___" . . . "[76FFB4BFE677]" . "Glycosyltransferase prediction in Mycobacterium tuberculosis genome by threading"@cs . "14310" . "Glycosyltransferase prediction in Mycobacterium tuberculosis genome by threading"@en . . . "Mycobacterium tuberculosis is a intracellular pathogen of the alveolar macrophages in lung resistant to most common antibiotics and chemotherapeutic agents. This resistance is related to its unusual and well-organized cell wall that contains the unique structures of branched and complex polysaccharides and glycolipids. The main cell wall constituents are known but there is only little information about the key enzymes in their biosynthesis, glycosyltransferases (GT). The genome of M. tuberculosis contains 3,951 protein-coding sequences. Putative function annotation of some of them was predicted using a combination of sequence alignment and motif comparison. Using this approach, only a small number of putative GTs was identified. Recently, only nine crystal structures of GTs have been solved. There is very low sequence similarity among them and they belong to different family groups. On the other hand, solving of their crystal structures demonstrated that they adopt only two basic 3D-folds We focused o"@en . "Glycosyltransferase prediction in Mycobacterium tuberculosis genome by threading"@cs . "2002-01-01+01:00"^^ . "Mycobacterium tuberculosis is a intracellular pathogen of the alveolar macrophages in lung resistant to most common antibiotics and chemotherapeutic agents. This resistance is related to its unusual and well-organized cell wall that contains the unique structures of branched and complex polysaccharides and glycolipids. The main cell wall constituents are known but there is only little information about the key enzymes in their biosynthesis, glycosyltransferases (GT). The genome of M. tuberculosis contains 3,951 protein-coding sequences. Putative function annotation of some of them was predicted using a combination of sequence alignment and motif comparison. Using this approach, only a small number of putative GTs was identified. Recently, only nine crystal structures of GTs have been solved. There is very low sequence similarity among them and they belong to different family groups. On the other hand, solving of their crystal structures demonstrated that they adopt only two basic 3D-folds We focused o" . "3rd International Symposium on Glycosyltransferases" . "RIV/00216224:14310/02:00007106" . . . . "Bettler, Emmanuel" . "Mycobacterium tuberculosis is a intracellular pathogen of the alveolar macrophages in lung resistant to most common antibiotics and chemotherapeutic agents. This resistance is related to its unusual and well-organized cell wall that contains the unique structures of branched and complex polysaccharides and glycolipids. The main cell wall constituents are known but there is only little information about the key enzymes in their biosynthesis, glycosyltransferases (GT). The genome of M. tuberculosis contains 3,951 protein-coding sequences. Putative function annotation of some of them was predicted using a combination of sequence alignment and motif comparison. Using this approach, only a small number of putative GTs was identified. Recently, only nine crystal structures of GTs have been solved. There is very low sequence similarity among them and they belong to different family groups. On the other hand, solving of their crystal structures demonstrated that they adopt only two basic 3D-folds We focused o"@cs . . "1"^^ . "Stockholm" . "Imberty, Anne" . . . "Wimmerov\u00E1, Michaela" . "Z(MSM 143100005)" . "September 19 - 22, Djuronaset, Stockholm, Sweden" . "Glycosyltransferase prediction in Mycobacterium tuberculosis genome by threading" . . "Glycosyltransferase prediction in Mycobacterium tuberculosis genome by threading"@en . "Lund University" . "112" . "647228" . .