. . "10"^^ . . "Results of treatment of childhood chronic ITP"@en . "Scripta medica" . . "Chronic childhood idiopathic (immune) thrombocytopenic purpura (ITP) is relatively rare, accounting only for 10-20% of children with ITP. Its treatment is very difficult. The therapeutic modalities are the following: steroids (high-dose or pulse therapy, high-dose immunoblobulin, interferon, anti-D immunoglobulin, cytotoxic immunosuppressives (azathioprine), splenectomy, etc. A group of 37 children with chronic ITP was treated during the last ten years in the First Department of Pediatrics. We used all above-mentioned curative options except of anti-D immunoglobulin. The permanent increase of the platelet count over 10x10/9/l as most often reached after splenectomy (11 children), cytotoxic immunosuppressives (4 children), steroids (2 children) and interferonu alpha 2a (2 children). The 2 children treated with interferon had even the permanent platelet count above 150x10/9/l. Regarding the undesireble side-effects of some therapy (splenectomy, storoids, cytotoxic immunosuppressives), we recomend to use" . . . "RIV/00216224:14110/98:00003839!RIV/2002/MZ0/141102/N" . "Results of treatment of childhood chronic ITP" . . "782490" . "39" . . . "14110" . "Bajer, Milan" . "1" . . "71" . "1211-3395" . "RIV/00216224:14110/98:00003839" . "Hrstkov\u00E1, Hana" . . "CZ - \u010Cesk\u00E1 republika" . "P(IZ3710)" . "Results of treatment of childhood chronic ITP"@en . "[FB840A47EEBF]" . . . "Results of treatment of childhood chronic ITP"@en . "2"^^ . . "0"^^ . "Chronic childhood idiopathic (immune) thrombocytopenic purpura (ITP) is relatively rare, accounting only for 10-20% of children with ITP. Its treatment is very difficult. The therapeutic modalities are the following: steroids (high-dose or pulse therapy, high-dose immunoblobulin, interferon, anti-D immunoglobulin, cytotoxic immunosuppressives (azathioprine), splenectomy, etc. A group of 37 children with chronic ITP was treated during the last ten years in the First Department of Pediatrics. We used all above-mentioned curative options except of anti-D immunoglobulin. The permanent increase of the platelet count over 10x10/9/l as most often reached after splenectomy (11 children), cytotoxic immunosuppressives (4 children), steroids (2 children) and interferonu alpha 2a (2 children). The 2 children treated with interferon had even the permanent platelet count above 150x10/9/l. Regarding the undesireble side-effects of some therapy (splenectomy, storoids, cytotoxic immunosuppressives), we recomend to use"@en . "2"^^ . "0"^^ . "Results of treatment of childhood chronic ITP" .