"3"^^ . "35929" . "1211-264X" . . "Pathophysiology and pathogenesis of Salmonella sepsis"@en . "Patofyziologie a patogeneze salmonelov\u00E9 sepse"@cs . "Pathophysiology; Salmonella enteritidis; Sepsis"@en . "Patofyziologie a patogeneze salmonelov\u00E9 sepse" . "CZ - \u010Cesk\u00E1 republika" . "RIV/00216224:14110/14:00075809" . "Pathophysiology and pathogenesis of Salmonella sepsis"@en . "Husa, Petr" . . . "RIV/00216224:14110/14:00075809!RIV15-MSM-14110___" . "Patofyziologie a patogeneze salmonelov\u00E9 sepse"@cs . . . "Klinick\u00E1 mikrobiologie a infek\u010Dn\u00ED l\u00E9ka\u0159stv\u00ED" . "Patofyziologie a patogeneze salmonelov\u00E9 sepse" . . . "Auto\u0159i p\u0159edkl\u00E1daj\u00ED p\u0159ehled sou\u010Dasn\u00FDch znalost\u00ED o komplexn\u00EDch palogenetick\u00FDch a patolyziologick\u00FDch mechanizmech v\u00FDznamn\u00FDch pro rozvoj sepse p\u0159i salmonel\u00F3ze. Zm\u00EDn\u011Bna je aktivace NOD like receplor\u016F lipopolysacharidem, \u00FAnik lyzosoni\u00E1ln\u00ED degradaci a vznik tzv. intracelul\u00E1rn\u00ED replika\u010Dni niky, vliv na reorganizaci cytoskeletu, indukce proapoptotick\u00FDch mechanizm\u016F, zm\u011Bna hladin n\u011Bkter\u00FDch cytoki nu (IL-lbeta, TNF-alfa-(x) a funkce a v\u00FDznam omptinov\u00FDch prote\u00E1z."@cs . . "Auto\u0159i p\u0159edkl\u00E1daj\u00ED p\u0159ehled sou\u010Dasn\u00FDch znalost\u00ED o komplexn\u00EDch palogenetick\u00FDch a patolyziologick\u00FDch mechanizmech v\u00FDznamn\u00FDch pro rozvoj sepse p\u0159i salmonel\u00F3ze. Zm\u00EDn\u011Bna je aktivace NOD like receplor\u016F lipopolysacharidem, \u00FAnik lyzosoni\u00E1ln\u00ED degradaci a vznik tzv. intracelul\u00E1rn\u00ED replika\u010Dni niky, vliv na reorganizaci cytoskeletu, indukce proapoptotick\u00FDch mechanizm\u016F, zm\u011Bna hladin n\u011Bkter\u00FDch cytoki nu (IL-lbeta, TNF-alfa-(x) a funkce a v\u00FDznam omptinov\u00FDch prote\u00E1z." . "4"^^ . "I" . "Pol\u00E1k, Pavel" . "The authors present a review of current knowledge about complex pathogenetic and pathophysiologic mechanisms involved in the development of sepsis in salmonellosis. Mechanisms such as lipopolysacharide-induced NOD-like receptor activation, escaping lysosomal degradation, intracellular replication niche formation, cytoskeleton reorganization, proapoptotic mechanism induction, changes in cytokine levels (IL-1beta, TNF-alfa) and function of omptin proteases are discussed."@en . "20" . . . . . . . . "Jur\u00E1nkov\u00E1, Jana" . "[AF3AC39AA576]" . "14110" . "3"^^ . "1" . .