"[647E7B266855]" . . . "000333494100006" . "14110" . . . . "Medical Hypotheses" . . . . "0306-9877" . "Ne\u010Des\u00E1nek, Ivo" . "3" . . . . "4"^^ . . "Epigenetic changes are generally based on the switching of alternative functional or structural states and result in the adaptation of cellular expression patterns during proliferation, differentiation or plastic changes in the adult organism, whereas some epigenetic information can be passed on other generations while other is not. Hence, the principal question is: why is some information reset or resolved during the meiosis process and other is passed from one generation to another, or, in other words: what %22adaptation trigger%22 level initiates transgenerationally transmitted epigenome change? Hereto, we propose a theory which states that stress, or, more specifically, the energy cost of an individual's adaptation to stress, represents a viable candidate for the transgenerational transmission trigger of a given acquired trait." . . "Bienertov\u00E1-Va\u0161k\u016F, Julie" . "RIV/00216224:14110/14:00075489" . . "%22Stress entropic load%22 as a transgenerational epigenetic response trigger" . "I, P(ED2.1.00/03.0101), Z(MZ0MOU2005)" . "Zl\u00E1mal, Filip" . "RIV/00216224:14110/14:00075489!RIV15-MSM-14110___" . "ALLOSTASIS; PLASTICITY"@en . "Epigenetic changes are generally based on the switching of alternative functional or structural states and result in the adaptation of cellular expression patterns during proliferation, differentiation or plastic changes in the adult organism, whereas some epigenetic information can be passed on other generations while other is not. Hence, the principal question is: why is some information reset or resolved during the meiosis process and other is passed from one generation to another, or, in other words: what %22adaptation trigger%22 level initiates transgenerationally transmitted epigenome change? Hereto, we propose a theory which states that stress, or, more specifically, the energy cost of an individual's adaptation to stress, represents a viable candidate for the transgenerational transmission trigger of a given acquired trait."@en . . "10.1016/j.mehy.2013.12.008" . . "Vinkl\u00E1rek, Jan" . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . . "5"^^ . . "%22Stress entropic load%22 as a transgenerational epigenetic response trigger"@en . . "%22Stress entropic load%22 as a transgenerational epigenetic response trigger" . "5"^^ . . "47743" . "%22Stress entropic load%22 as a transgenerational epigenetic response trigger"@en . . "82" . "Nov\u00E1k, Jan" .