. "Formation of Secretory Senescent Cells in Prostate Tumors: The Role of Androgen Receptor Activity and Cell Cycle Regulation" . "The induction of senescence in cancer cells is believed to be a potent mechanism of tumor suppression; however, senescent cells remain metabolically active and secrete a broad spectrum of factors, modulate the tissue microenvironment, and potentially promote tumorigenicity in neighboring malignant cells. Another important subpopulation of secretory cells modulating the prostate tissue microenvironment is represented by neuroendocrine cells. Interestingly, androgen deprivation therapy, a widely used treatment for advanced prostate cancer, induces both the emergence of neuroendocrine-like prostate cancer cells and the senescence-associated secretory phenotype in prostate cancer epithelial cells."@en . . "Dordrecht" . . "The induction of senescence in cancer cells is believed to be a potent mechanism of tumor suppression; however, senescent cells remain metabolically active and secrete a broad spectrum of factors, modulate the tissue microenvironment, and potentially promote tumorigenicity in neighboring malignant cells. Another important subpopulation of secretory cells modulating the prostate tissue microenvironment is represented by neuroendocrine cells. Interestingly, androgen deprivation therapy, a widely used treatment for advanced prostate cancer, induces both the emergence of neuroendocrine-like prostate cancer cells and the senescence-associated secretory phenotype in prostate cancer epithelial cells." . "9789400759572" . . "324"^^ . . "Springer Science+Business Media" . . "Formation of Secretory Senescent Cells in Prostate Tumors: The Role of Androgen Receptor Activity and Cell Cycle Regulation"@en . "3"^^ . . . "Pernicov\u00E1, Zuzana" . "2"^^ . "75526" . "Formation of Secretory Senescent Cells in Prostate Tumors: The Role of Androgen Receptor Activity and Cell Cycle Regulation"@en . "prostate cancer; senescence; neuroendocrine differentiation; senescence-associated secretory phenotype; androgen receptor; Skp2"@en . . . "14"^^ . "P(ED1.100/02/0123), Z(MSM0021622430)" . . . "Sou\u010Dek, Karel" . . "Va\u0148hara, Petr" . . . . "RIV/00216224:14110/13:00068061!RIV14-MSM-14110___" . "Formation of Secretory Senescent Cells in Prostate Tumors: The Role of Androgen Receptor Activity and Cell Cycle Regulation" . "[3B1FC98AEB36]" . . . "RIV/00216224:14110/13:00068061" . . "10.1007/978-94-007-5958-9_26" . . "Tumor Dormancy, Quiescence and Senescence" . . "14110" . . "Aging, Cancer, and Noncancer Pathologies, Vol. 1" .