"14110" . . . . . . "Pediatrie pro praxi" . . "175011" . . . "Transient hyperphosphatasemia"@en . "Tranzitorn\u00ED hyperfosfatazemie" . . "Tranzitorn\u00ED hyperfosfatazemie"@cs . "Dole\u017Eel, Zden\u011Bk" . "Tranzitorn\u00ED hyperfosfatazemie" . . "Tranzitorn\u00ED hyperfosfatazemie (TH) je charakterizov\u00E1na izolovan\u00FDm zv\u00FD\u0161en\u00EDm s\u00E9rov\u00E9 koncentrace alkalick\u00E9 fosfat\u00E1zy (ALP-s) p\u0159i sou\u010Dasn\u00E9 absenci klinick\u00FDch a laboratorn\u00EDch n\u00E1lez\u016F dokl\u00E1daj\u00EDc\u00EDch onemocn\u011Bn\u00ED jater nebo skeletu. TH se nej\u010Dast\u011Bji popisuje u d\u011Bt\u00ED v pr\u016Fb\u011Bhu prvn\u00EDch p\u011Bti rok\u016F \u017Eivota. Zv\u00FD\u0161en\u00ED ALP-s je u TH p\u0159echodn\u00E9 a b\u011Bhem n\u011Bkolika m\u011Bs\u00EDc\u016F se koncentrace vrac\u00ED do norm\u00E1ln\u00EDho rozmez\u00ED hodnot. TH nevy\u017Eaduje \u017E\u00E1dnou l\u00E9\u010Dbu. Je uveden klinick\u00FD pr\u016Fb\u011Bh TH u batolete a p\u0159ehled liter\u00E1rn\u00EDch \u00FAdaj\u016F. D\u011Bt\u0161t\u00ED l\u00E9ka\u0159i by m\u011Bli na TH v r\u00E1mci diferenci\u00E1ln\u011B diagnostick\u00FDch \u00FAvah pom\u00FD\u0161let, nebo\u0165 diagnostika je relativn\u011B jednoduch\u00E1 a d\u011Bti nen\u00ED nutn\u00E9 zat\u011B\u017Eovat n\u011Bkter\u00FDmi slo\u017Eit\u00FDmi a n\u00E1ro\u010Dn\u00FDmi vy\u0161et\u0159ovac\u00EDmi anal\u00FDzami." . "I" . "Transient hyperphosphatasemia"@en . . . "RIV/00216224:14110/12:00060704" . "alkaline phosphatase; transient hyperphosphatasemia; childhood"@en . . "Tranzitorn\u00ED hyperfosfatazemie"@cs . "4"^^ . "Tranzitorn\u00ED hyperfosfatazemie (TH) je charakterizov\u00E1na izolovan\u00FDm zv\u00FD\u0161en\u00EDm s\u00E9rov\u00E9 koncentrace alkalick\u00E9 fosfat\u00E1zy (ALP-s) p\u0159i sou\u010Dasn\u00E9 absenci klinick\u00FDch a laboratorn\u00EDch n\u00E1lez\u016F dokl\u00E1daj\u00EDc\u00EDch onemocn\u011Bn\u00ED jater nebo skeletu. TH se nej\u010Dast\u011Bji popisuje u d\u011Bt\u00ED v pr\u016Fb\u011Bhu prvn\u00EDch p\u011Bti rok\u016F \u017Eivota. Zv\u00FD\u0161en\u00ED ALP-s je u TH p\u0159echodn\u00E9 a b\u011Bhem n\u011Bkolika m\u011Bs\u00EDc\u016F se koncentrace vrac\u00ED do norm\u00E1ln\u00EDho rozmez\u00ED hodnot. TH nevy\u017Eaduje \u017E\u00E1dnou l\u00E9\u010Dbu. Je uveden klinick\u00FD pr\u016Fb\u011Bh TH u batolete a p\u0159ehled liter\u00E1rn\u00EDch \u00FAdaj\u016F. D\u011Bt\u0161t\u00ED l\u00E9ka\u0159i by m\u011Bli na TH v r\u00E1mci diferenci\u00E1ln\u011B diagnostick\u00FDch \u00FAvah pom\u00FD\u0161let, nebo\u0165 diagnostika je relativn\u011B jednoduch\u00E1 a d\u011Bti nen\u00ED nutn\u00E9 zat\u011B\u017Eovat n\u011Bkter\u00FDmi slo\u017Eit\u00FDmi a n\u00E1ro\u010Dn\u00FDmi vy\u0161et\u0159ovac\u00EDmi anal\u00FDzami."@cs . "4"^^ . "RIV/00216224:14110/12:00060704!RIV13-MSM-14110___" . "Pape\u017E, Jan" . "Transient hyperphosphatasemia (TH) of infancy and childhood is a temporary and isolated increase of serum alkaline phosphatase (ALP-s) activity occurring without obvious cause usually during the first five years of life. The diagnosis of TH is established after finding of a transient but marked ALP-s elevation in the absence of clinical or laboratory findings of bone or liver disease. ALP-s returns to normal in a few months. TH has not been found to be life-threatening and is classified as a benign phenomenon. We report a clinical case of a toddler with TH and a literature review. This condition should be recognized by pediatricians in order not to put patiens throught lengthy, expensive and unnecessary investigation."@en . . "CZ - \u010Cesk\u00E1 republika" . "13" . . "1213-0494" . "4" . . . "3"^^ . "[DDE34C9E7BE6]" . "R\u00E1\u010Dilov\u00E1, Zde\u0148ka" . "Pinkasov\u00E1, Tereza" . .