"0042-773X" . "Eyelids with yellow granulomas and cough \u2013 periocular xanthogranuloma associated with adult-onset asthma. A case study and an overview of clinical forms of juvenile xanthogranuloma and its therapy"@en . . "O\u010Dn\u00ED v\u00ED\u010Dka se \u017Elut\u00FDmi granulomy a ka\u0161el - periokul\u00E1rn\u00ED xanthogranulom dosp\u011Bl\u00FDch spojen\u00FD s astmatem. Popis p\u0159\u00EDpadu a p\u0159ehled klinick\u00FDch forem juveniln\u00EDho xantogranulomu a terapie" . . . "155748" . . . . . . . . "P(NT11154), S, Z(MSM0021622434)" . "[4906D64D12AC]" . "Moty\u010Dkov\u00E1, Iva" . "\u0158eh\u00E1k, Z." . . . "11"^^ . "Vnit\u0159n\u00ED l\u00E9ka\u0159stv\u00ED" . . . "14"^^ . . . . "Histiocytic diseases caused by proliferation and accumulation of phagocytosing macrophages (foamy macrophages) have many clinical forms. These are classified under \u201Cjuvenile xanthogranuloma\u201D within the WHO classification of blood disorders. Localized forms with benign course include normolipaemic xanthomatosis, xanthogranuloma and necrobiotic xanthogranuloma. Disseminated forms in children take a form of so called \u201Cdisseminated juvenile xanthogranuloma\u201D or Erdheim-Chester disease in adults. We describe a case of a patient who, at 53 years of age, first noticed yellow granulomas on her eyelids. The disease progressed gradually and, at 59, affects the eyelids as well as their closest surroundings. According to MR and PET-CT, the disease gradually infiltrated the inside of the orbit, orbital fat as well as extraocular muscles and started to cause exoftalmus of one of the eyes. Propagation of the xanthogranuloma into the orbit and infiltration of extraocular muscles might impair eye function."@en . . . "14110" . . . "Kr\u00E1l, Zden\u011Bk" . . "Krej\u010D\u00ED, Marta" . . . "Szturz, Petr" . "Histiocyt\u00E1rn\u00ED choroby zp\u016Fsoben\u00E9 proliferac\u00ED a akumulac\u00ED fagocytuj\u00EDc\u00EDch makrof\u00E1g\u016F (p\u011Bnit\u00FDch makrof\u00E1g\u016F) maj\u00ED velmi mnoho klinick\u00FDch podob. Dle WHO klasifikace krevn\u00EDch chorob jsou \u0159azeny do skupiny s ozna\u010Den\u00EDm \u201Ejuveniln\u00ED xantogranulom\u201C. K lokalizovan\u00FDm form\u00E1m s benign\u00EDm pr\u016Fb\u011Bhem pat\u0159\u00ED normolipemick\u00E1 xantomat\u00F3za, xantogranulom a nekrobiotick\u00FD xantogranulom. Diseminovan\u00E9 formy u d\u011Bt\u00ED nab\u00FDvaj\u00ED formy tzv. \u201Ediseminovan\u00E9ho juveniln\u00EDho xantogranulomu\u201C, u dosp\u011Bl\u00FDch pak Erdheimovy-Chesterovy nemoci. Popisujeme p\u0159\u00EDpad pacientky, kter\u00E1 si poprv\u00E9 ve v\u011Bku 53 let v\u0161imla \u017Elut\u00FDch granulom\u016F na v\u00ED\u010Dk\u00E1ch. Choroba pozvolna progredovala a ve v\u011Bku 59 let postihuje nejen v\u00ED\u010Dka, ale i jejich nejbli\u017E\u0161\u00ED okol\u00ED. Choroba dle MR a PET-CT zobrazen\u00ED postupn\u011B infiltruje nitro orbity, orbit\u00E1ln\u00ED tuk i okohybn\u00E9 svaly a za\u010Dala ji\u017E zp\u016Fsobovat exoftalmus na jednom oku. Propagace xantogranulomu do nitra orbity a infiltrace okohybn\u00FDch sval\u016F m\u016F\u017Ee naru\u0161it funkce oka. Pacientka si v posledn\u00EDm roce st\u011B\u017Eovala na ka\u0161el." . "CZ - \u010Cesk\u00E1 republika" . "Vesel\u00FD, Karel" . "5" . "Mayer, Ji\u0159\u00ED" . "RIV/00216224:14110/12:00060421" . "Koukalov\u00E1, R." . . "Pour, Lud\u011Bk" . . "Histiocyt\u00E1rn\u00ED choroby zp\u016Fsoben\u00E9 proliferac\u00ED a akumulac\u00ED fagocytuj\u00EDc\u00EDch makrof\u00E1g\u016F (p\u011Bnit\u00FDch makrof\u00E1g\u016F) maj\u00ED velmi mnoho klinick\u00FDch podob. Dle WHO klasifikace krevn\u00EDch chorob jsou \u0159azeny do skupiny s ozna\u010Den\u00EDm \u201Ejuveniln\u00ED xantogranulom\u201C. K lokalizovan\u00FDm form\u00E1m s benign\u00EDm pr\u016Fb\u011Bhem pat\u0159\u00ED normolipemick\u00E1 xantomat\u00F3za, xantogranulom a nekrobiotick\u00FD xantogranulom. Diseminovan\u00E9 formy u d\u011Bt\u00ED nab\u00FDvaj\u00ED formy tzv. \u201Ediseminovan\u00E9ho juveniln\u00EDho xantogranulomu\u201C, u dosp\u011Bl\u00FDch pak Erdheimovy-Chesterovy nemoci. Popisujeme p\u0159\u00EDpad pacientky, kter\u00E1 si poprv\u00E9 ve v\u011Bku 53 let v\u0161imla \u017Elut\u00FDch granulom\u016F na v\u00ED\u010Dk\u00E1ch. Choroba pozvolna progredovala a ve v\u011Bku 59 let postihuje nejen v\u00ED\u010Dka, ale i jejich nejbli\u017E\u0161\u00ED okol\u00ED. Choroba dle MR a PET-CT zobrazen\u00ED postupn\u011B infiltruje nitro orbity, orbit\u00E1ln\u00ED tuk i okohybn\u00E9 svaly a za\u010Dala ji\u017E zp\u016Fsobovat exoftalmus na jednom oku. Propagace xantogranulomu do nitra orbity a infiltrace okohybn\u00FDch sval\u016F m\u016F\u017Ee naru\u0161it funkce oka. Pacientka si v posledn\u00EDm roce st\u011B\u017Eovala na ka\u0161el."@cs . . "\u0160toura\u010Dov\u00E1, J." . "O\u010Dn\u00ED v\u00ED\u010Dka se \u017Elut\u00FDmi granulomy a ka\u0161el - periokul\u00E1rn\u00ED xanthogranulom dosp\u011Bl\u00FDch spojen\u00FD s astmatem. Popis p\u0159\u00EDpadu a p\u0159ehled klinick\u00FDch forem juveniln\u00EDho xantogranulomu a terapie" . "Eyelids with yellow granulomas and cough \u2013 periocular xanthogranuloma associated with adult-onset asthma. A case study and an overview of clinical forms of juvenile xanthogranuloma and its therapy"@en . "58" . . "13"^^ . . "O\u010Dn\u00ED v\u00ED\u010Dka se \u017Elut\u00FDmi granulomy a ka\u0161el - periokul\u00E1rn\u00ED xanthogranulom dosp\u011Bl\u00FDch spojen\u00FD s astmatem. Popis p\u0159\u00EDpadu a p\u0159ehled klinick\u00FDch forem juveniln\u00EDho xantogranulomu a terapie"@cs . "Zahradov\u00E1, Lenka" . "foamy histiocytes; juvenile xathogranuloma; adult onset asthma and periocular xanthogranuloma; necrobiotic xanthogranuloma; Erdheim-Chester disease; monoclonal gammopathy; 2-chlorodeoxyadenosin; cladribin; thalidomid; lenalidomid"@en . . "O\u010Dn\u00ED v\u00ED\u010Dka se \u017Elut\u00FDmi granulomy a ka\u0161el - periokul\u00E1rn\u00ED xanthogranulom dosp\u011Bl\u00FDch spojen\u00FD s astmatem. Popis p\u0159\u00EDpadu a p\u0159ehled klinick\u00FDch forem juveniln\u00EDho xantogranulomu a terapie"@cs . . "Adam, Zden\u011Bk" . . "Van\u00ED\u010Dek, Ji\u0159\u00ED" . . . . "H\u00E1jek, Roman" . "RIV/00216224:14110/12:00060421!RIV13-MZ0-14110___" . .