"Experimental Administration of the Probiotic Escherichia coli Strain Nissle 1917 Results in Decreased Diversity of E. coli Strains in Pigs"@en . "Kune\u0161, Martin" . . "0343-8651" . "Chaloupkov\u00E1, Eva" . "Kop\u00E1\u010Dov\u00E1, Marcela" . "Kohoutov\u00E1, Darina" . "\u0160marda, Jan" . "Bure\u0161, Jan" . "I, P(NS9665), Z(MSM0021622415)" . "64" . "11"^^ . . . "10.1007/s00284-011-0051-x" . . . "Escherichia coli; pig; strain Escherichia coli Nissle 1917"@en . "RIV/00216224:14110/12:00059148!RIV13-MZ0-14110___" . . "\u0160majs, David" . . "Rejchrt, Stanislav" . "135513" . "Current Microbiology" . "Experimental Administration of the Probiotic Escherichia coli Strain Nissle 1917 Results in Decreased Diversity of E. coli Strains in Pigs"@en . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . . . "The strain Escherichia coli Nissle 1917 (EcN) is widely used as an efficient probiotic in therapy and prevention of human infectious diseases, especially of the intestinal system. Concurrently, small adult pigs are being used as experimental omnivore models to study human gastrointestinal functions. EcN bacteria were applied to 6 adult healthy female pigs in a 2-week trial. 6 Control animals remained untreated. Altogether, 164 and 149 bacterial strains were isolated from smear samples taken from gastrointestinal mucosa in the experimental and control group, respectively. Each individual E. coli strain was then tested for the presence of 29 bacteriocin-encoding determinants as well as for DNA markers of A, B1, B2 and D phylogenetic groups. A profound reduction of E. coli genetic variance (from 32 variants to 13 ones, P = 0.0006) was found in the experimental group, accompanied by a lower incidence of bacteriocin producers in the experimental group when compared to control (21.3 and 34."@en . "F\u00F6rstl, Miroslav" . . . "The strain Escherichia coli Nissle 1917 (EcN) is widely used as an efficient probiotic in therapy and prevention of human infectious diseases, especially of the intestinal system. Concurrently, small adult pigs are being used as experimental omnivore models to study human gastrointestinal functions. EcN bacteria were applied to 6 adult healthy female pigs in a 2-week trial. 6 Control animals remained untreated. Altogether, 164 and 149 bacterial strains were isolated from smear samples taken from gastrointestinal mucosa in the experimental and control group, respectively. Each individual E. coli strain was then tested for the presence of 29 bacteriocin-encoding determinants as well as for DNA markers of A, B1, B2 and D phylogenetic groups. A profound reduction of E. coli genetic variance (from 32 variants to 13 ones, P = 0.0006) was found in the experimental group, accompanied by a lower incidence of bacteriocin producers in the experimental group when compared to control (21.3 and 34." . . . "Experimental Administration of the Probiotic Escherichia coli Strain Nissle 1917 Results in Decreased Diversity of E. coli Strains in Pigs" . "Experimental Administration of the Probiotic Escherichia coli Strain Nissle 1917 Results in Decreased Diversity of E. coli Strains in Pigs" . . "000300769800001" . "[560A26C228EC]" . "6"^^ . "RIV/00216224:14110/12:00059148" . . "Lesn\u00E1, Ji\u0159ina" . . . "14110" . . . "Kv\u011Btina, Jaroslav" . "3"^^ . . "3" . .