. . "Celogenomov\u00E9 sekvena\u010Dn\u00ED metody: srovn\u00E1n\u00ED 3 metod p\u0159i sekvenaci genomu Treponema pallidum subspecies pertenue Samoa D." . "14110" . "Treponema pallidum subsp. pertenue, p\u016Fvodce tropick\u00E9ho ko\u017En\u00EDho onemocn\u011Bn\u00ED yaws, nelze morfologicky, serologicky ani imunologicky odli\u0161it od poddruhu pallidum, p\u016Fvodce venerologick\u00E9ho onemocn\u011Bn\u00ED syfilis (Treponema pallidum subsp. pallidum). K ur\u010Den\u00ED podstaty rozd\u00EDl\u016F v klinick\u00E9 manifestaci obou onemocn\u011Bn\u00ED byla stanovena kompletn\u00ED nukleotidov\u00E1 sekvence genomu T. pallidum subsp. pertenue. Sekvenace genomu Treponema pallidum subsp. pertenue Samoa D byla provedena metodou komparativn\u00ED genomov\u00E9 sekvenace (CGS, NimbleGen), pyrosekvencov\u00E1n\u00EDm (454 Life Sciences) a metodou firmy Solexa. Sekvence jednotliv\u00FDch metod pak byly zp\u011Btn\u011B porovn\u00E1ny s kompletn\u00ED sekvenc\u00ED. Celkov\u00E1 d\u00E9lka genomu kmene Samoa D je 1 139 296 bp. Vyhodnocen\u00ED po\u010Dtu chyb bylo provedeno jen v m\u00EDstech genomu, kde se sekvence v\u0161ech metod p\u0159ekr\u00FDvaly a mimo oblasti tpr gen\u016F." . . "Celogenomov\u00E9 sekvena\u010Dn\u00ED metody: srovn\u00E1n\u00ED 3 metod p\u0159i sekvenaci genomu Treponema pallidum subspecies pertenue Samoa D."@cs . . "Strouhal, Michal" . "Treponema pallidum subsp. pertenue, p\u016Fvodce tropick\u00E9ho ko\u017En\u00EDho onemocn\u011Bn\u00ED yaws, nelze morfologicky, serologicky ani imunologicky odli\u0161it od poddruhu pallidum, p\u016Fvodce venerologick\u00E9ho onemocn\u011Bn\u00ED syfilis (Treponema pallidum subsp. pallidum). K ur\u010Den\u00ED podstaty rozd\u00EDl\u016F v klinick\u00E9 manifestaci obou onemocn\u011Bn\u00ED byla stanovena kompletn\u00ED nukleotidov\u00E1 sekvence genomu T. pallidum subsp. pertenue. Sekvenace genomu Treponema pallidum subsp. pertenue Samoa D byla provedena metodou komparativn\u00ED genomov\u00E9 sekvenace (CGS, NimbleGen), pyrosekvencov\u00E1n\u00EDm (454 Life Sciences) a metodou firmy Solexa. Sekvence jednotliv\u00FDch metod pak byly zp\u011Btn\u011B porovn\u00E1ny s kompletn\u00ED sekvenc\u00ED. Celkov\u00E1 d\u00E9lka genomu kmene Samoa D je 1 139 296 bp. Vyhodnocen\u00ED po\u010Dtu chyb bylo provedeno jen v m\u00EDstech genomu, kde se sekvence v\u0161ech metod p\u0159ekr\u00FDvaly a mimo oblasti tpr gen\u016F."@cs . "P(GA310/07/0321), P(NR8967), Z(MSM0021622415)" . . . "RIV/00216224:14110/08:00024753!RIV10-MZ0-14110___" . . . . . "Celogenomov\u00E9 sekvena\u010Dn\u00ED metody: srovn\u00E1n\u00ED 3 metod p\u0159i sekvenaci genomu Treponema pallidum subspecies pertenue Samoa D." . "Treponema pallidum ssp. pertenue, the causative agent of tropical dermal disease yaws can not be morphologically, serologically nor immunologically distinguished from subspecies pallidum, the causative agent of venereal disease syphilis. To elucidate genetic background of the differences in clinical manifestations of both diseases, complete genome sequence of T. pallidum ssp. pertenue was determined. For genome sequencing of Treponema pallidum ssp. pertenue Samoa D, comparative genome sequencing (CGS, NimbleGen), pyrosequencing (454 Life Sciences) and Solexa sequencing technology were used. Sequences of all three methods were eventually compared to the complete genome sequence. The size of Samoa D strain genome is 1,139,296 bp. Numbers of errors were determined in cases where data from all three methods was available (tpr genes were excluded). Lasergene software was used for processing of the sequences."@en . . "Whole genome sequencing methods: comparison of 3 methods used in the sequencing of Treponema pallidum subspecies pertenue Samoa D genome."@en . "CGS; pyrosequencing; Solexa"@en . "\u010Cejkov\u00E1, Darina" . . "Celogenomov\u00E9 sekvena\u010Dn\u00ED metody: srovn\u00E1n\u00ED 3 metod p\u0159i sekvenaci genomu Treponema pallidum subspecies pertenue Samoa D."@cs . . . "359061" . . "5"^^ . . . . "RIV/00216224:14110/08:00024753" . "5"^^ . "\u0160majs, David" . "[CD3B42F5980F]" . "Posp\u00ED\u0161ilov\u00E1, Petra" . "Zoban\u00EDkov\u00E1, Marie" . . . . . "Whole genome sequencing methods: comparison of 3 methods used in the sequencing of Treponema pallidum subspecies pertenue Samoa D genome."@en .