"In this paper, the effect of modification of the cross-linked collagen I with hyaluronic acid, hydroxyapatite nanoparticles and chitosan nanofibers on the mechanical response of the compact scaffold material and the lyophilized porous scaffold construct has been investigated in the dry state at 37 oC under tensile loading. The results showed that the addition of hyaluronic acid reduced the tensile elastic modulus and slightly increased the ultimate deformation of crosslinked collagen I under the test conditions used. On the other hand, addition of hydroxyapatite nanoparticles and chitosan nanofibers, respectively, increased the elastic modulus of the modified collagen ten-fold and four-fold, respectively. The ultimate tensile deformation has been decreased by hydroxyapatite and increased by the chitosan nanofibers."@en . "0862-8408" . . "Amler, Ev\u017Een" . "CZ - \u010Cesk\u00E1 republika" . . . . . "14110" . "000252436800003" . "5"^^ . . "Krupa, Petr" . . . "56" . . . . . "8"^^ . . "[BC52490CD790]" . "In this paper, the effect of modification of the cross-linked collagen I with hyaluronic acid, hydroxyapatite nanoparticles and chitosan nanofibers on the mechanical response of the compact scaffold material and the lyophilized porous scaffold construct has been investigated in the dry state at 37 oC under tensile loading. The results showed that the addition of hyaluronic acid reduced the tensile elastic modulus and slightly increased the ultimate deformation of crosslinked collagen I under the test conditions used. On the other hand, addition of hydroxyapatite nanoparticles and chitosan nanofibers, respectively, increased the elastic modulus of the modified collagen ten-fold and four-fold, respectively. The ultimate tensile deformation has been decreased by hydroxyapatite and increased by the chitosan nanofibers." . . "9"^^ . "Physiological Research" . "RIV/00216224:14110/07:00024236" . . "Ne\u010Das, Alois" . "Chitosan; Nanofibers; Hyaluronic acid; Hydroxyapatite; Mesenchymal stem cells; Joint resurfacing"@en . . . "Mechanical response of porous scaffolds for cartilage engineering" . "G\u00E1l, Petr" . "P(1ET400110403), P(2B06130), P(IAA500390702), Z(AV0Z50390512), Z(MSM0021630501)" . . . . . "Pl\u00E1nka, Ladislav" . "Mechanical response of porous scaffolds for cartilage engineering"@en . "432585" . . "Mechanical response of porous scaffolds for cartilage engineering"@en . "Suppl. 1" . "Mechanical response of porous scaffolds for cartilage engineering" . . "Kecov\u00E1, Helga" . "RIV/00216224:14110/07:00024236!RIV10-MSM-14110___" . "Jan\u010D\u00E1\u0159, Josef" . "Slovikova, Alexandra" . . . . .