. "0306-9877" . "We have formalized extracellular and intracellular volume interaction with each other and the influence of these processes on the type of cell growth. The linearized model was verified by stereo metric solution and the results were compared with experimental data. Two theoretical solutions were found: Solution 1, extracellular volume (ECV) was calculated to be about 23% of total body volume (TV). Stereo metric solution suggested the cubic cell cluster formed by 8-cells. This hypothesis (Solution l) explains the ECV to be compatible with the widely accepted value (about 23% of TV). In addition, the 8-cell cluster hypothesis explains the existence of ECV oscillation with the period of about seven days. This hypothesis probably describes the dominant type of growth in humans. Solution 2, in this type of growth, ECV fills about 77% per cent of TV. Instead of the 8-cell cube, in this type of proliferation 4-cells could form a tetrahedron."@en . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "4"^^ . "Kol\u00E1\u0159, Petr" . . . . "H\u00E1jek, Dobroslav" . . "Extracellular volume regulation and growth"@en . . "growth; extracellular volume"@en . "RIV/00216224:14110/05:00013612!RIV10-MZ0-14110___" . . . . . . . "Extracellular volume regulation and growth" . "We have formalized extracellular and intracellular volume interaction with each other and the influence of these processes on the type of cell growth. The linearized model was verified by stereo metric solution and the results were compared with experimental data. Two theoretical solutions were found: Solution 1, extracellular volume (ECV) was calculated to be about 23% of total body volume (TV). Stereo metric solution suggested the cubic cell cluster formed by 8-cells. This hypothesis (Solution l) explains the ECV to be compatible with the widely accepted value (about 23% of TV). In addition, the 8-cell cluster hypothesis explains the existence of ECV oscillation with the period of about seven days. This hypothesis probably describes the dominant type of growth in humans. Solution 2, in this type of growth, ECV fills about 77% per cent of TV. Instead of the 8-cell cube, in this type of proliferation 4-cells could form a tetrahedron." . . "\u0160tarha, Pavel" . . . "64" . . "Medical Hypotheses" . "[04F242BDE090]" . "14110" . "4"^^ . . "521271" . "Maini, Philip" . "RIV/00216224:14110/05:00013612" . "P(NK7730), P(VS96097), S, Z(MSM 141100002)" . "Extracellular volume regulation and growth"@en . . "Extracellular volume regulation and growth" . "2"^^ . . "2" .