. . . . "31" . . "Role of genetic variability in systems of receptor-mediated and enzymatic defence against glycation in long-term consequences of diabetes mellitus"@en . . "diabetes mellitus; complications; polymorphism; glycation; AGE; methylglyoxal"@en . "Diabetes mellitus is the most common metabolic disease with late complications due to chronic hyperglycaemia. Altered carbohydrate and lipid metabolism together with impaired detoxification of carbonyl substrates and impaired trapping of oxygen radicals are responsible for diabetic cell damage. Variable functional capacity of detoxifying systems could contribute to different susceptibility to develop complications. Identification of genetic variants responsible for modulating relevant intermediate phenotype in diabetic milieu could help to define individual risk-profile and to modify therapeutic strategy accordingly." . . "Biochemical Society Transactions" . . . "Role of genetic variability in systems of receptor-mediated and enzymatic defence against glycation in long-term consequences of diabetes mellitus" . . "Role geneticke variabilty v systemech zajistujicich receptory-zprostredkovanou a enzymatickou obranu proti glykaci v patogenezi pozdnich komplikaci diabetu mellitus"@cs . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . . "Diabetes mellitus is the most common metabolic disease with late complications due to chronic hyperglycaemia. Altered carbohydrate and lipid metabolism together with impaired detoxification of carbonyl substrates and impaired trapping of oxygen radicals are responsible for diabetic cell damage. Variable functional capacity of detoxifying systems could contribute to different susceptibility to develop complications. Identification of genetic variants responsible for modulating relevant intermediate phenotype in diabetic milieu could help to define individual risk-profile and to modify therapeutic strategy accordingly."@en . "RIV/00216224:14110/03:00008104!RIV09-GA0-14110___" . "Role of genetic variability in systems of receptor-mediated and enzymatic defence against glycation in long-term consequences of diabetes mellitus" . . "Role of genetic variability in systems of receptor-mediated and enzymatic defence against glycation in long-term consequences of diabetes mellitus"@en . "000187289000060" . "Ka\u0148kov\u00E1, Kate\u0159ina" . "3"^^ . . "14110" . "RIV/00216224:14110/03:00008104" . . "Prehledny clanekshrnuje poznatky o roli geneticke variabilty v systemech zajistujicich receptory-zprostredkovanou a enzymatickou obranu proti glykaci v patogenezi pozdnich komplikaci diabetu mellitus."@cs . . . "6" . "P(GP303/02/D127), Z(MSM 141100002)" . "1"^^ . . "[00A0F7D8D126]" . "1"^^ . "Role geneticke variabilty v systemech zajistujicich receptory-zprostredkovanou a enzymatickou obranu proti glykaci v patogenezi pozdnich komplikaci diabetu mellitus"@cs . . "625886" . . "0300-5127" . .