"Extracelul\u00E1rn\u00ED matrix je tvo\u0159ena pod\u00E9l regeneruj\u00EDc\u00EDch axon\u016F v pleten\u00E9 nervov\u00E9 prot\u00E9ze."@cs . "Regeneration; Peripheral nerve; Extracellular matrix; Immunohistochemistry"@en . "2"^^ . "10"^^ . "P(GA309/00/0407)" . "Scripta medica" . "14110" . "The extracellular matrix formed in a knitted prosthesis, which was applied between the stumps of a transected sciatic nerve of the rat, was investigated to find out whether it provided suitable conditions for nerve regeneration. After 6 weeks, the prosthesis contained a nerve outgrowth connecting the nerve stumps. The immunohistochemical staining of the cryostat sections through the middle of the nerve prosthesis revealed that thrombospondin, fibronectin, chondroitin sulfate A and C, and type IV collagen were localised in the connective tissue surrounding the nerve outgrowth, in the perineurium of individual minifascicles, as well as in the endoneurium among regenerated nerve fibres. No immunostaining for vitronectin was observed in cross-sections through the nerve outgrowth. Our results suggest that the environment formed during nerve regrowth within a knitted prosthesis provides conditions supporting the regeneration of nerve fibres."@en . . "1211-3395" . "2"^^ . "74" . . "Immunohistochemical study of the extracellular matrix formed during peripheral nerve regeneration through a knitted prosthesis" . "The extracellular matrix formed in a knitted prosthesis, which was applied between the stumps of a transected sciatic nerve of the rat, was investigated to find out whether it provided suitable conditions for nerve regeneration. After 6 weeks, the prosthesis contained a nerve outgrowth connecting the nerve stumps. The immunohistochemical staining of the cryostat sections through the middle of the nerve prosthesis revealed that thrombospondin, fibronectin, chondroitin sulfate A and C, and type IV collagen were localised in the connective tissue surrounding the nerve outgrowth, in the perineurium of individual minifascicles, as well as in the endoneurium among regenerated nerve fibres. No immunostaining for vitronectin was observed in cross-sections through the nerve outgrowth. Our results suggest that the environment formed during nerve regrowth within a knitted prosthesis provides conditions supporting the regeneration of nerve fibres." . "[0FDC93251E7C]" . "Immunohistochemical study of the extracellular matrix formed during peripheral nerve regeneration through a knitted prosthesis" . "Immunohistochemical study of the extracellular matrix formed during peripheral nerve regeneration through a knitted prosthesis"@en . "Imunohistochemick\u00E1 studie ECM b\u011Bhem regenerace perifern\u00EDho nervu p\u0159es pletenou prot\u00E9zu"@cs . . . "Dubov\u00FD, Petr" . . . . "Imunohistochemick\u00E1 studie ECM b\u011Bhem regenerace perifern\u00EDho nervu p\u0159es pletenou prot\u00E9zu"@cs . "CZ - \u010Cesk\u00E1 republika" . "RIV/00216224:14110/01:00005656" . . . "Hradilov\u00E1 Sv\u00ED\u017Eensk\u00E1, Ivana" . . . "Immunohistochemical study of the extracellular matrix formed during peripheral nerve regeneration through a knitted prosthesis"@en . . . "682413" . . . "3" . . . "RIV/00216224:14110/01:00005656!RIV09-GA0-14110___" .