. "[F0C4985BAC91]" . . "z\u00E1\u0159\u00ED 2000, Freising-Weihenstephan, BRD" . "P(GA303/00/D062)" . "Antiradical phenolic compounds from Cynara cardunculus"@en . . "2000-01-01+01:00"^^ . "Bocho\u0159\u00E1kov\u00E1, Hana" . "In Polyphenols Communication 2000. XX th International Conference on Polyphenols" . . . . . "Slanina, Ji\u0159\u00ED" . "704839" . "Extracts from artichoke (Cynara scolymus L.) or cardoon (Cynara cardunculus L., Asteraceae), are widely used in phytotherapy as choleretic, hypocholesterolemic and hepatoprotective agents (Kraft, 1997). The cholesterol-lowering effect of artichoke extracts was confirmed by numerous animal experiments and recently by a controlled clinical trial. The possible mechanism of hypocholesterolemic activity involves choleretic action, reduction of cholesterol biosynthesis and inhibition of low density lipoprotein oxidation (Pittler and Ernst, 1998). The antiatherosclerotic and antihepatotoxic activities can be mediated by antioxidative action of the artichoke extract. These activities have been ascribed to the phenolic compounds present in the extract. According to HPLC analysis, the methanol extract of C. cardunculus leaves contained three main phenolic components, 5-caffeoylquinic acid (chlorogenic acid), 1,5-dicaffeoylquinic acid (1,5-DiCQA) and flavonoid luteolin-7-O-glucoside. However, caffeoylquinic acid"@en . "Antiradical phenolic compounds from Cynara cardunculus"@cs . "2"^^ . . "RIV/00216224:14110/00:00003561" . "4"^^ . . "S.Martens, D.Treutter, G.Forkmann, str.425" . "4"^^ . . "Extracts from artichoke (Cynara scolymus L.) or cardoon (Cynara cardunculus L., Asteraceae), are widely used in phytotherapy as choleretic, hypocholesterolemic and hepatoprotective agents (Kraft, 1997). The cholesterol-lowering effect of artichoke extracts was confirmed by numerous animal experiments and recently by a controlled clinical trial. The possible mechanism of hypocholesterolemic activity involves choleretic action, reduction of cholesterol biosynthesis and inhibition of low density lipoprotein oxidation (Pittler and Ernst, 1998). The antiatherosclerotic and antihepatotoxic activities can be mediated by antioxidative action of the artichoke extract. These activities have been ascribed to the phenolic compounds present in the extract. According to HPLC analysis, the methanol extract of C. cardunculus leaves contained three main phenolic components, 5-caffeoylquinic acid (chlorogenic acid), 1,5-dicaffeoylquinic acid (1,5-DiCQA) and flavonoid luteolin-7-O-glucoside. However, caffeoylquinic acid"@cs . "Paulov\u00E1, Hana" . . . "14110" . "Freising-Weihenstephan, BRD" . . . "Antiradical phenolic compounds from Cynara cardunculus" . . . . "T\u00E1borsk\u00E1, Eva" . "RIV/00216224:14110/00:00003561!RIV09-GA0-14110___" . . "Antiradical phenolic compounds from Cynara cardunculus"@cs . "Antiradical phenolic compounds from Cynara cardunculus" . "Antiradical; phenolics; Cynara cardunculus; DPPH"@en . "Extracts from artichoke (Cynara scolymus L.) or cardoon (Cynara cardunculus L., Asteraceae), are widely used in phytotherapy as choleretic, hypocholesterolemic and hepatoprotective agents (Kraft, 1997). The cholesterol-lowering effect of artichoke extracts was confirmed by numerous animal experiments and recently by a controlled clinical trial. The possible mechanism of hypocholesterolemic activity involves choleretic action, reduction of cholesterol biosynthesis and inhibition of low density lipoprotein oxidation (Pittler and Ernst, 1998). The antiatherosclerotic and antihepatotoxic activities can be mediated by antioxidative action of the artichoke extract. These activities have been ascribed to the phenolic compounds present in the extract. According to HPLC analysis, the methanol extract of C. cardunculus leaves contained three main phenolic components, 5-caffeoylquinic acid (chlorogenic acid), 1,5-dicaffeoylquinic acid (1,5-DiCQA) and flavonoid luteolin-7-O-glucoside. However, caffeoylquinic acid" . "Antiradical phenolic compounds from Cynara cardunculus"@en . . .