. . . "000087981300012" . "RIV/00216224:14110/00:00002245!RIV09-MSM-14110___" . "2000" . "U dvaceti psychiatrick\u00FDch pacient\u016F byly sledov\u00E1ny jejich genotypy a fenotypy."@cs . . . . "RIV/00216224:14110/00:00002245" . . "Z(MSM 141100001)" . "Vojt\u00ED\u0161kov\u00E1, Marie" . "Starobova, Olga" . "4" . "[41A656FDA89F]" . . "Hyksov\u00E1, Marie" . "0885-6222" . "5"^^ . "Effects of psychopharmacotherapy on phenotypic expression of cytochrome P450 2D6 in patients genotyped for CYP2D6 mutations" . "Effects of psychopharmacotherapy on phenotypic expression of cytochrome P450 2D6 in patients genotyped for CYP2D6 mutations"@cs . . "Twenty psychiatric patients were investigated for their CYP2D6 genotype and phenotype. Eight patients were pretreated with CYP2D6 substrate drugs, another 12 were therapy free. Genotyping with PCR for mutations in exon 3, 4 and 5 of CYP2D6 gene detected 65% of patients as heterozygously mutated in exon 4. The phenotyping test showed a significantly higher occurence of poor metabolizers in patients" . . "CZ - \u010Cesk\u00E1 republika" . . "3"^^ . "14110" . "Effects of psychopharmacotherapy on phenotypic expression of cytochrome P450 2D6 in patients genotyped for CYP2D6 mutations"@en . . "709845" . "Human Psychopharmacol." . . "Twenty psychiatric patients were investigated for their CYP2D6 genotype and phenotype. Eight patients were pretreated with CYP2D6 substrate drugs, another 12 were therapy free. Genotyping with PCR for mutations in exon 3, 4 and 5 of CYP2D6 gene detected 65% of patients as heterozygously mutated in exon 4. The phenotyping test showed a significantly higher occurence of poor metabolizers in patients"@en . "4"^^ . "McCaskey Hada\u0161ov\u00E1, Eva" . "Effects of psychopharmacotherapy on phenotypic expression of cytochrome P450 2D6 in patients genotyped for CYP2D6 mutations" . . "Effects of psychopharmacotherapy on phenotypic expression of cytochrome P450 2D6 in patients genotyped for CYP2D6 mutations"@cs . . "Pharmacogenetics; CYP2D6 polymorphism; Dextromethorphan; Psychotropics"@en . . . "Effects of psychopharmacotherapy on phenotypic expression of cytochrome P450 2D6 in patients genotyped for CYP2D6 mutations"@en . . . "\u010Ce\u0161kov\u00E1, Eva" .